Browsing by Author "Bijan"
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Publication Necrotizing Enterocolitis and Anasarca: Unusual Presentation of Multisystem Inflammatory Syndrome in Neonates – A case Report(Nepal Paediatric Society (JNPS), 2024) SK, Md Habibullah; Zamal, Ashadur; BijanAbstract: Multisystem inflammatory syndrome in neonates (MIS-N) is a rare complication of COVID-19, characterized by immune dysregulation leading to various systemic manifestations. We present a case of a preterm neonate with MIS-N who developed necrotizing enterocolitis (NEC) and anasarca. Despite initial challenges in diagnosis, MIS-N was suspected based on clinical presentation and confirmed by laboratory findings, including elevated inflammatory markers and positive SARS-CoV-2 antibodies in the infant and the mother. Management involved immunomodulatory therapy with IVIG and methylprednisolone, resulting in clinical improvement. This case underscores the importance of considering MIS-N in symptomatic neonates born to mothers with a history of COVID-19, particularly in the post-pandemic era.