Publication: Necrotizing Enterocolitis and Anasarca: Unusual Presentation of Multisystem Inflammatory Syndrome in Neonates – A case Report
Files
Date
2024
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Multisystem inflammatory syndrome in neonates (MIS-N) is a rare complication of COVID-19, characterized by immune dysregulation leading to various systemic manifestations. We present a case of a preterm neonate with MIS-N who developed necrotizing enterocolitis (NEC) and anasarca. Despite initial challenges in diagnosis, MIS-N was suspected based on clinical presentation and confirmed by laboratory findings, including elevated inflammatory markers and positive SARS-CoV-2 antibodies in the infant and the mother. Management involved immunomodulatory therapy with IVIG and methylprednisolone, resulting in clinical improvement. This case underscores the importance of considering MIS-N in symptomatic neonates born to mothers with a history of COVID-19, particularly in the post-pandemic era.
Description
Md Habibullah SK
Senior Resident, Department of Neonatology, IPGME&R and SSKM Hospital, SSKM Hospital Rd, Bhowanipore, Kolkata, West Bengal 700020, India.
Ashadur Zamal
Post Doctoral Trainee, Department of Neonatology, IPGME&R and SSKM Hospital, SSKM Hospital Rd, Bhowanipore, Kolkata, West Bengal 700020, India.
Bijan
Associate Professor, Department of Neonatology, IPGME&R and SSKM Hospital, SSKM Hospital Rd, Bhowanipore, Kolkata, West Bengal 700020, India.
Keywords
Multisystem Inflammatory Syndrome in Neonates (MIS-N), Necrotizing Enterocolitis, Anasarca, SARS-CoV-2