Browsing by Author "Ghimire, Ranjeet"
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Publication Pharmacotherapy of Hospitalized Patients with COVID-19 at a Tertiary Care Hospital in Nepal(Institute of Medicine, Tribhuvan University, 2025) Mudvari, Anish; Prasad, Pravin; Pokharel, Akritee; Thapaliya, Sabin; Maharjan, Bindira; Khadka, Rebanta; Lamsal, Arun Batsa; Ghimire, Ranjeet; Bista, ApekshaABSTRACT: Introduction The COVID-19 pandemic poses a major health threat with no standardized treatments for SARS-CoV-2. This study evaluates pharmacotherapy trends in COVID-19 patients during the second wave at a tertiary care facility. Methods A retrospective, observational, cross-sectional study was conducted in a tertiary care centre, utilising patient data from April 2021 to July 2021. The sample included 310 patients admitted with a confirmed diagnosis of COVID-19. Patients were classified based on oxygen requirement levels, and data were analysed using descriptive statistics. Results Of the 310 patients, 59% were male and 41% female, with a mean age of 53.37 ± 17.01 years. The average hospital stay was 10 ± 7.15 days. Most patients (66.8%) required supplemental oxygen, and 7.4% required mechanical ventilation. The majority received antibacterial therapy (307, 99.03%), with ceftriaxone being the most commonly prescribed antibiotic (73.22%). Remdesivir was the predominant antiviral, and dexamethasone was used in 88.39% of patients. Conclusion Antibiotic use was extensive among hospitalised COVID-19 patients, with ceftriaxone being the most common. Antiviral use was less frequent, with Remdesivir being the preferred choice. Dexamethasone played a crucial role in managing severe cases.