Publication: Pharmacotherapy of Hospitalized Patients with COVID-19 at a Tertiary Care Hospital in Nepal
Date
2025
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Medicine, Tribhuvan University
Abstract
ABSTRACT:
Introduction
The COVID-19 pandemic poses a major health threat with no
standardized treatments for SARS-CoV-2. This study evaluates
pharmacotherapy trends in COVID-19 patients during the second
wave at a tertiary care facility.
Methods
A retrospective, observational, cross-sectional study was conducted
in a tertiary care centre, utilising patient data from April 2021 to July
2021. The sample included 310 patients admitted with a confirmed
diagnosis of COVID-19. Patients were classified based on oxygen
requirement levels, and data were analysed using descriptive
statistics.
Results
Of the 310 patients, 59% were male and 41% female, with a mean
age of 53.37 ± 17.01 years. The average hospital stay was 10 ± 7.15
days. Most patients (66.8%) required supplemental oxygen, and 7.4%
required mechanical ventilation. The majority received antibacterial
therapy (307, 99.03%), with ceftriaxone being the most commonly
prescribed antibiotic (73.22%). Remdesivir was the predominant
antiviral, and dexamethasone was used in 88.39% of patients.
Conclusion
Antibiotic use was extensive among hospitalised COVID-19
patients, with ceftriaxone being the most common. Antiviral use
was less frequent, with Remdesivir being the preferred choice.
Dexamethasone played a crucial role in managing severe cases.
Description
Anish Mudvari
Maharajgunj Medical Campus, Tribhuvan University
Author
https://orcid.org/0000-0002-0509-2982
Pravin Prasad
Author
Akritee Pokharel
Author
Sabin Thapaliya
Author
Bindira Maharjan
Author
Rebanta Khadka
Author
Arun Batsa Lamsal
Author
Ranjeet Ghimire
Author
Apeksha Bista
Author
Keywords
COVID-19, pharmacotherapy, antibacterial, remdesivir, dexamethasone, Nepal, hospitalized patients