Browsing by Author "Gurung, D"
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Publication Apocrine Carcinoma Developing in a Naevus Sebaceous of Scalp(Kathmandu University, 2012) Paudel, U; Jha, A; Pokhrel, DB; Gurung, D; Parajuli, S; Pant, AABSTRACT Apocrine skin carcinoma is an aggressive cutaneous tumour. We report a case of apocrine carcinoma developing in a naevus sebaceous of scalp in a 45 years old male. Malignant transformation of Naevus sebaceous is a rare complication usually found in elderly patients. Most of these tumours are basal cell carcinoma or squamous cell carcinoma. Only few cases of apocrine carcinoma on naevus sebaceous have been previously reported. This report highlights the potential of naevus sebaceous for malignant transformation. KEY WORDS Apocrine, Basal cell carcinoma, carcinoma, hamartoma, nevus, Sebaceous of Jadassohn, skin.Publication Assessment of Oral Health and Nutritional Status of School Teachers in Dharamshala City, Himachal Pradesh(Kathmandu University, 2024) Gurung, D; Bhardwaj, VK; Fotedar, S; Thakur, AS; Vashisth, SABSTRACT Background Nutrition is associated with oral health and any changes in dietary habits have impacted nutritional profiles which in turn influences oral health status. Objective To assess the oral health and nutritional status among school teachers in Dharamshala city, Himachal Pradesh. Method A descriptive cross-sectional study was undertaken with interviews and documented using a structured and adapted WHO proforma. The oral health was assessed by using WHO oral assessment form 2013 (by tooth surfaces) and the nutritional status by using five day dietary recall and scored according to dental health dietary score. The dental health dietary scores included food group scores (FGS), nutritional evaluation score (NES), decay promoting potential scores (DPPS) for all five days. Result Almost, two third of the school teachers in both types of schools had an excellent Food Group Score (FGS) on all five days of dietary recalls. The mean total Decay Promoting Potential Score (DPPS) was 23.33±3.20 (minute). Approximately one- third of the teachers in both types of schools had DPPS scores within the “watch out” zone of dietary recall, ranging 15 or more on each day. The mean DMFT was 3.79±2.52 with mean total decayed teeth as 1.35±2.03. Similarly, the mean DMFS was 9.68±7.95 with the mean total decayed surfaces as 1.81±2.94. Conclusion The frequency of essential food groups remained consistent throughout the five- day dietary recall period. Carbohydrates formed the primary component whereas proteins were frequently missing from the diets. Frequent absence of protein intake in diet increased loss of attachment. KEY WORDS Nutritional status, Oral health status, WHO oral assessment for adultsPublication Multi-drug Resistant and Extended Spectrum β-lactamase Producing Salmonella Species Isolated from Fresh Chicken Liver Samples(Kathmandu University, 2020) Adhikari, S; Khadka, S; Sapkota, S; Sharma, BR; Ghimire, A; Chalise, M; Gurung, D; Kunwar, SABSTRACT Background Emergence of antibiotic resistance among microbes contaminating the fresh meat products is a global public health concern as they can be easily transmitted to humans through their consumption and contact. Objective The current study was conducted to determine the distribution of antimicrobial resistance among Salmonella species isolated from fresh chicken liver samples with special emphasis on extended spectrum beta-lactamase (ESBL) production. Method A total of 200 fresh chicken liver samples were cultivated for the isolation of Salmonella and further subcultivated to detect extended spectrum beta-lactamase production among them. Antimicrobial susceptibility testing (AST) was done by disk diffusion method using a panel of 7 antimicrobials. Result Out of 200 samples analyzed, 61 (30.5%) samples harbored Salmonella species out of which 15 (7.5%) samples showed the presence of Salmonella Typhi. A significant association was noted in the incidence of Salmonella with various factors pertaining to the butchers, such as age, sex, literacy rate, practices of washing knives and chopping board, wearing aprons and gloves and type of water used (p < 0.05). Salmonella isolates were highly sensitive to amikacin (82.0%) and least sensitive to tetracycline (3.3%). All the isolates were resistant to colistin. Sixty (98.4%) isolates were identified as multi-drug resistant (MDR). The total number of extended spectrum beta- lactamase producers reported among Salmonella isolates was 29 (47.5%). Conclusion The results indicate that the fresh chicken liver samples sold in Bharatpur Metropolis are reservoirs of multi-drug resistant Salmonella, including extended spectrum beta- lactamase producers, that could potentially be transmitted to the humans by direct contact or through inadequate cooking. KEY WORDS Antimicrobial susceptibility testing, Extended spectrum beta-lactamase, Fresh chicken liver samples, Multi-drug resistant, SalmonellaPublication Pattern Of Skin Diseases In A Rural Village Development Community of Nepal(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2014) Shrestha, R; Shrestha, DP; Lama, L; Gurung, D; Rosdahl, IAbstract: Introduction: Skin diseases are a common cause of morbidity in Nepal as per the health services report. There is limited information on the prevalence and pattern of skin diseases in the community. The objective of this study was to determine the pattern of skin diseases in a rural village development community of Nepal. Materials and methods: Two dermatologic health camps were conducted, during which, the villagers were examined by dermatologists. The skin diseases diagnosed were recorded in a proforma. Results: There were 433 individuals examined and 359 (male-47.9%; female-52.1%) had skin disease identified clinically (camp prevalence- 83%). The age of patients ranged from 1 to 80 years (mean-24.5; SD±15.9), with majority in the age group of 10-19 years. The most common skin disease category was eczemas (36.4%), followed by infections (28.4%), acne (22%), pigment disorders (34%) and urticaria (12.3%). Conclusion: Skin diseases were common in the community. The five most common Skin disease categories were eczemas, infections, acne and pigment disorders were the more common conditions. Keywords: Acne, eczema, infection, pattern of skin diseases, pigment disorder, village development communityPublication Profile of Vitiligo in Western Nepal(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2010) Kumar, A; Neupane, S; Parajuli, S; Gurung, DAbstract Background Vitiligo is common worldwide. The highest incidence is reported from Indian subcontinent. However, there are only few studies available on epidemiology of vitiligo from Nepal Objective To determine the clinical patterns of vitiligo, the associated sociodemographic factors and its associated disorders among patients attending dermatology outpatient department of Manipal Teaching Hospital, Gandaki Medical College Teaching Hospital and Fishtail Hospital and Research Center Pokhara. Methods All patients presenting with signs and symptoms suggestive of vitiligo over a period of one-year (from march 2009 to march 2010 ) at the out-patient clinics in the Dermatology Department of Manipal Teaching Hospital, Gandaki Medical College Teaching Hospital and Fishtail Hospital and Research Center, Pokhara were included in the study. Socio-demographic details regarding age, sex, marital status, education and occupation were recorded .A detailed clinical history related to the presenting complain and clinical examination findings were recorded. Relevant available investigations were ordered based on signs and symptoms to determine if any associated disorders. Results Two hundred and twenty four patients with clinical diagnosis of vitiligo were studied. Males constituted 102 (45%) patients and females 122 (55%) of the total number of patients. Duration of disease at the time of presentation ranged from two weeks to 40 years. The lower limb was the initial site of onset of vitiligo in majority 77 (34.37%) of the patients, followed by the upper limbs, head and neck, trunk and mucosae in decreasing order of frequency. The commonest clinical pattern found was vitiligo vulgaris followed by acrofacial, segmental and mucosal types. Lesions showing leukotrichia were observed in 40 (18.87%) patients and koebnerization was observed in 42 (18.75%) patients. Eleven children had halo nevi. Associated abnormalities included alopecia areata (13 patients), diabetes mellitus (12 patients) and one patient had atopic dermatitis. A positive family history was obtained in 14(6.25%) of the patients. Conclusion Vitiligo vulgaris is on of the common clinical-type skin disorder observed in Nepal. There w e re associated disorders/abnormalities in some patients such as alopecia areata , diabetes mellitus and atopic dermatitis. Keywords Clinical Profile; Vitiligo; Western Nepal.Publication Psoriasis: Clinical and Epidemiological Features in a Hospital Based Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2012) Shrestha, D P; Gurung, DNA Keywords: Psoriasis, prevalence, clinical types, ethnic distribution, age at onset, age at first medical visit, Nepal