Browsing by Author "KC, Mathura"
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Publication Clinical profile of typhoid patients(Kathmandu University, 2003) KC, Mathura; Gurubacharya, DL; Shrestha, A; Pant, S; Basnet, P; Karki, DBObjective: The present study was undertaken to determine the clinical profile of typhoid fever in hospitalised patients. Design: Prospective cross-sectional study. Setting: Kathmandu Medical College and Teaching Hospital Method: Total of thirty patients above fifteen years of age who had clinical features strongly suggestive of typhoid fever and on blood culture found to be positive for salmonella typhi were analysed for clinical features. Result: Among total of thirty cases, there were 17 (57%) males and 13(43%) females. 86% of cases of typhoid fever clustered around 15-30 years of age. Predominant symptoms were fever (100%), headache (90%), abdominal Pain (37%) and constipation (33%). Common clinical signs were splenomegaly (37%), relative bradycardia (27%) and hepatomegaly (17%). None of the patients presented with complications. Conclusion: The clinical profile of typhoid fever in our study revealed not much difference from that of other studies on typhoid fever. Rose spots were not noticed and we did not find a single case of complication of typhoid fever. Probably early initiation of antibiotics prevented the complications. Key words: Typhoid fever, S. Typhi.Publication Injection drug use and tricuspid valve endocarditis(Kathmandu University, 2005) KC, Mathura; Thapa, N; Rauniyar, A; Magar, A; Gurubachharya, DL; Karki, DBTricuspid valve endocarditis is more common in injection drug users. Pulmonary valve and Eustachian valve endocarditis have been reported but are very rare. Earlier reports of endocarditis in injection drug users emphasized the dominance of right sided involvement. In a series of 105 patients 86 % were right sided and 14 % had left sided involvement. We report a case of isolated tricuspid valve endocarditis in an injection drug user affecting a structurally normal heart and review of the literature on this subject. Key Words: injection drug use, tricuspid valve endocarditis