Publication: Clinical profile of typhoid patients
Date
2003
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
Objective: The present study was undertaken to determine the clinical profile of typhoid fever in hospitalised
patients. Design: Prospective cross-sectional study. Setting: Kathmandu Medical College and Teaching Hospital
Method: Total of thirty patients above fifteen years of age who had clinical features strongly suggestive of typhoid
fever and on blood culture found to be positive for salmonella typhi were analysed for clinical features. Result:
Among total of thirty cases, there were 17 (57%) males and 13(43%) females. 86% of cases of typhoid fever
clustered around 15-30 years of age. Predominant symptoms were fever (100%), headache (90%), abdominal Pain
(37%) and constipation (33%). Common clinical signs were splenomegaly (37%), relative bradycardia (27%) and
hepatomegaly (17%). None of the patients presented with complications. Conclusion: The clinical profile of typhoid
fever in our study revealed not much difference from that of other studies on typhoid fever. Rose spots were not
noticed and we did not find a single case of complication of typhoid fever. Probably early initiation of antibiotics
prevented the complications.
Key words: Typhoid fever, S. Typhi.