Browsing by Author "Pokhrel, Khilasa"
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Publication Methicillin-resistant Staphylococcus aureus in Nepal(Nepal Medical Association, 2021) Shrestha, Lok Bahadur; Syangtan, Gopiram; Basnet, Ajaya; Acharya, Krishna Prasad; Chand, Arun Bahadur; Pokhrel, KhilasaAbstract: Staphylococcus aureus is both a frequent commensal and a leading cause of endocarditis, bacteremia, osteomyelitis and skin and soft tissue infections and device-related infections. We performed this minireview to summarize the prevalence of Staphylococcus aureus among clinical samples and estimate the proportion of methicillin-resistant Staphylococcus aureus. The prevalence of Staphylococcus aureus among clinical isolates in Nepal is 34.5%. On average, the proportion of multi-drug resistance in Staphylococcus aureus is 57.1%. Methicillin-resistant Staphylococcus aureus accounts for a total of 41.7%. Inducible clindamycin resistance was detected in about 35% of the isolates. A regular antimicrobial resistance surveillance mechanism is necessary to mitigate the development of resistance among organisms and further spread of superbugs like methicillin-resistance Staphylococcus aureus.