Publication: Methicillin-resistant Staphylococcus aureus in Nepal
Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Staphylococcus aureus is both a frequent commensal and a leading cause of endocarditis, bacteremia, osteomyelitis and skin and soft tissue infections and device-related infections. We performed this minireview to summarize the prevalence of Staphylococcus aureus among clinical samples and estimate the proportion of methicillin-resistant Staphylococcus aureus. The prevalence of Staphylococcus aureus among clinical isolates in Nepal is 34.5%. On average, the proportion of multi-drug resistance in Staphylococcus aureus is 57.1%. Methicillin-resistant Staphylococcus aureus accounts for a total of 41.7%. Inducible clindamycin resistance was detected in about 35% of the isolates. A regular antimicrobial resistance surveillance mechanism is necessary to mitigate the development of resistance among organisms and further spread of superbugs like methicillin-resistance Staphylococcus aureus.
Description
Lok Bahadur Shrestha
School of Medical Sciences and The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia
https://orcid.org/0000-0002-0054-0715
Gopiram Syangtan
Tribhuvan University, Shi-Gan International College of Science and Technology, Kathmandu, Nepal
Ajaya Basnet
Tribhuvan University, Shi-Gan International College of Science and Technology, Kathmandu, Nepal
Krishna Prasad Acharya
Animal Quarantine Office, Budhanilkantha, Kathmandu, Nepal
Arun Bahadur Chand
Department of Clinical Laboratory, Kist Medical College & Teaching Hospital, Kathmandu, Nepal
Khilasa Pokhrel
Department of Microbiology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal
Keywords
clindamycin, methicillin-resistant Staphylococcus aureus, multi drug resistance