Browsing by Author "Rai, N"
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Publication Status of Hypertension and Its Associated Factors Among Undergraduate Medical Students of a Private Medical College in Lalitpur District(Kathmandu University, 2025) Sah, SK; Singh, N; Pandey, S; Sherpa (Lama), AT; Panta, PP; Shah, S; Ghising, K; Rai, NABSTRACT Background Hypertension, a significant global health concern, warrants exploration within the unique context of medical student populations. Hypertension is a silent killer and is a leading cause of premature morbidity and mortality particularly in developing countries including Nepal. Medical students are prone to stress, long working hours, unsteady and unhealthy lifestyles such as lack of exercise, eating unhealthy food which are high risk factors contributing to hypertension. Objective To assess the prevalence of hypertension and its associated risk factors among undergraduate medical students. Method A Cross-sectional study was conducted between August to November 2023 among the undergraduate medical students from first-year to final-year and interns at a teaching hospital after obtaining ethical approval from the Institutional Review Committee. A total enumeration sampling technique was used. Chi square test was used to determine the association between variable and P value less than 0.05 was fixed for statistically significant. Result Out of 500 participants, 234 (46.80%) were reported to have hypertension according to the classification of the American Heart Association, 2023. Among them, 169 (72.22%) were male and 65 (27.78%) were female, with a male-to-female ratio of 2.6:1. Male participants had significantly higher odds of developing hypertension compared to females, with a crude odds ratio (COR) of 3.116 (95% CI: 2.144–4.53, p < 0.001) and an adjusted odds ratio (AOR) of 2.815 (95% CI: 1.914–4.139, p < 0.001). Participants categorized as “Obese” also had significantly higher odds of developing hypertension compared to “Non-obese” individuals, with a COR of 1.862 (95% CI: 1.189–2.916, p = 0.006) and an AOR of 1.636 (95% CI: 1.026–2.607, p = 0.039). Conclusion The high frequency of hypertension in this study could indicate a hidden epidemic among medical students. The results suggest that effective health screening and routine examinations are necessary, in addition to measures that support healthy lifestyles. KEY WORDS Alcohol consumption, Blood pressure, Hypertension, Obesity, Sex, Smoking habitPublication Thrombolysis with Tenecteplase for Basilar Artery Occlusion in Neuro and Allied Clinic: Importance of Clinical Assessment and Drip and Ship Model in Nepal(Kathmandu University, 2024) Thapa, L; Ghimire, MR; Bhattarai, S; Shrestha, AM; Rai, N; Paudel, RABSTRACT Tenecteplase, a new thrombolytic drug, is now widely recommended and used for treating acute ischemic stroke, and timely thrombolysis within 4.5 hours is crucial for better outcomes. However, due to limited stroke awareness, transportation difficulties, and inadequate access to experts and comprehensive stroke care centers, fewer than 15% of stroke patients in Nepal receive thrombolytic therapy. The “drip and ship” model, which involves starting thrombolysis at a non- comprehensive stroke care center and transferring the patient to another center for further care, can effectively overcome these obstacles, provided trained personnel are available at non-comprehensive stroke care centers. We report a case of acute ischemic stroke treated with thrombolysis within 4.5 hours of symptom onset at a non-comprehensive stroke care center, followed by transfer to another center for ongoing care, demonstrating the feasibility and potential benefits of the drip and ship model in resource-limited settings. KEY WORDS Basilar artery occlusion, Drip and ship model, Tenecteplase, Thrombolysis