Publication: Thrombolysis with Tenecteplase for Basilar Artery Occlusion in Neuro and Allied Clinic: Importance of Clinical Assessment and Drip and Ship Model in Nepal
Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Tenecteplase, a new thrombolytic drug, is now widely recommended and used for
treating acute ischemic stroke, and timely thrombolysis within 4.5 hours is crucial
for better outcomes. However, due to limited stroke awareness, transportation
difficulties, and inadequate access to experts and comprehensive stroke care
centers, fewer than 15% of stroke patients in Nepal receive thrombolytic therapy.
The “drip and ship” model, which involves starting thrombolysis at a non-
comprehensive stroke care center and transferring the patient to another center for
further care, can effectively overcome these obstacles, provided trained personnel
are available at non-comprehensive stroke care centers. We report a case of acute
ischemic stroke treated with thrombolysis within 4.5 hours of symptom onset at a
non-comprehensive stroke care center, followed by transfer to another center for
ongoing care, demonstrating the feasibility and potential benefits of the drip and
ship model in resource-limited settings.
KEY WORDS
Basilar artery occlusion, Drip and ship model, Tenecteplase, Thrombolysis
Description
Thapa L,1,2 Ghimire MR,3 Bhattarai S,2 Shrestha AM,2 Rai N,4 Paudel R2
1Neuro and Allied Clinic (NC)
Anchalpur, Bhairahawa
2National Neuro Center (NNC)
Maharajgunj, Kathmandu
3Devdaha Medical College
Devdaha, Rupandehi
4KIST Medical College
Gwarko, Lalitpur
Keywords
Basilar artery occlusion, Drip and ship model, Tenecteplase, Thrombolysis