Browsing by Author "Sedhain, Sapana"
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Publication Histopathological Examination of CT-Guided Lung Biopsy in Patients Attending Tertiary Care Hospital, Nepal: A Cross-Sectional Study(Nepal APF Hospital, 2026) Sinha, Amrita; Sedhain, Sapana; Bhattarai, SooryaAbstract: Introduction: Among various lesions encountered in the lung, lung cancer is one of the most common cancers and a cause of cancer-related deaths. Among malignancies, non-small cell lung carcinoma is the most common lung cancer. A CT-guided lung biopsy is a quick, reliable, and simple technique with fewer complications than other methods for diagnosing pulmonary lesions. The main objective of this study was to evaluate the histopathological outcomes of CT- guided lung biopsies and to classify the identified lung lesions. Methods: This was a hospital-based, prospective, cross-sectional study conducted from 1st August 2023 to 31st January 2024, with ethical clearance from the Institutional Review Committee (IRC-PA-314/2023). A Convenience sampling included 73 patients. The obtained data were analyzed using Microsoft Excel and Statistical Package of the Social Sciences version 16. Results: The majority of cases with lung lesions were seen in the 71-80 years age group with male predominance. Of the 73 cases included in the study, neoplastic lesions comprised 56 (76.71%), followed by non-neoplastic lesions in 9 (12.33%), and inadequate biopsies in 8 (10.96%). Of the total 56 malignant lesions, the most common histological type was Non-Small Cell Lung Carcinoma, comprising 46 (82.14%), among which adenocarcinoma accounted for 30 (53.57%), followed by Squamous Cell Carcinoma accounting for 16 (28.57%). Conclusions: Lung tumors are quite common in patients presenting with a mass lesion. The most common histological type in this study was Adenocarcinoma.Publication Pattern of Fine Needle Aspiration Cytology of Head and Neck Swelling in Patients Attending a Tertiary Health Care Center: A Descriptive Cross-sectional Study(Nepal Medical Association, 2024) Bhattarai, Soorya; Sedhain, Sapana; Kafle, Neeta; Sinha, AmritaAbstract Introduction: Fine needle aspiration cytology is a simple, rapid, cost-effective method in diagnosis of head and neck swelling with minimal risk of complications. Head and neck swellings include a broad spectrum of diseases with different management for each. Fine needle aspiration cytology is a suitable and useful method for assessment of these swelling. This study was done with the objective to study the frequency and distribution of various head and neck lesions detected by fine needle aspiration cytology. Methods: A descriptive cross-sectional study was conducted at the Department of Pathology in a tertiary care center from February 1 to July 31, 2023 after obtaining ethical approval from Institutional Review Committee (Reference number: IRC-PA-191/2078-79). All the patients presenting with head and neck swelling during the study period were included in this study. Total sampling was done. Fine needle aspiration was done and cytological diagnosis was made. Descriptive analysis was done where frequency and percentage were calculated. Results: Out of 112 cases included in the study, 43 (38.40%) were of lymph nodes, 36 (32.14%) of thyroid, 22 (19.64%) of skin and soft tissue and 11 (9.82%) of salivary glands. Among the lymph nodes cases, there were 11 (25.57%) metastases. In thyroid lesions, beingn lesions were seen in 24 (66.68%). Conclusions: This study found that lymph nodes were the most common site for head and neck swellings, frequently involving metastatic lesions.