Publication: Histopathological Examination of CT-Guided Lung Biopsy in Patients Attending Tertiary Care Hospital, Nepal: A Cross-Sectional Study
Files
Date
2026
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal APF Hospital
Abstract
Abstract:
Introduction: Among various lesions encountered in the lung, lung cancer is one of the most common cancers and a cause of cancer-related deaths. Among malignancies, non-small cell lung carcinoma is the most common lung cancer. A CT-guided lung biopsy is a quick, reliable, and simple technique with fewer complications than other methods for diagnosing pulmonary lesions. The main objective of this study was to evaluate the histopathological outcomes of CT- guided lung biopsies and to classify the identified lung lesions.
Methods: This was a hospital-based, prospective, cross-sectional study conducted from 1st August 2023 to 31st January 2024, with ethical clearance from the Institutional Review Committee (IRC-PA-314/2023). A Convenience sampling included 73 patients. The obtained data were analyzed using Microsoft Excel and Statistical Package of the Social Sciences version 16.
Results: The majority of cases with lung lesions were seen in the 71-80 years age group with male predominance. Of the 73 cases included in the study, neoplastic lesions comprised 56 (76.71%), followed by non-neoplastic lesions in 9 (12.33%), and inadequate biopsies in 8 (10.96%). Of the total 56 malignant lesions, the most common histological type was Non-Small Cell Lung Carcinoma, comprising 46 (82.14%), among which adenocarcinoma accounted for 30 (53.57%), followed by Squamous Cell Carcinoma accounting for 16 (28.57%).
Conclusions: Lung tumors are quite common in patients presenting with a mass lesion. The most common histological type in this study was Adenocarcinoma.
Description
Amrita Sinha
Department of Pathology, Birat Medical College and Teaching Hospital, Tankisinuwari, Morang, Nepal.
Sapana Sedhain
Department of Pathology, Birat Medical College and Teaching Hospital, Tankisinuwari, Morang, Nepal.
https://orcid.org/0000-0002-9429-5043
Soorya Bhattarai
Department of Pathology, Birat Medical College and Teaching Hospital, Tankisinuwari, Morang, Nepal.
https://orcid.org/0000-0002-4870-2672
Keywords
adenocarcinoma, biopsy, squamous cell carcinoma