Browsing by Author "Shrestha, Elisha"
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Publication A Clinico-histopathological Diagnosis of Trichoadenomas on Nose: A Case report Authors(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2025) Shrestha, Elisha; Pradhan, Namrata; Thapa, Diksha; KC, Sharnawi; Karn, DharmendraAbstract: Trichoadenoma of Nikolowski is a slow-growing, well-differentiated, rare, benign tumor closely resembling the infundibular portion of the hair follicle. Reporting such cases adds to the limited literature and helps clinicians better recognize and understand the condition. Due to its clinical and histopathological resemblance to other skin tumors, accurate diagnosis can be challenging. Reporting cases aids in refining diagnostic approaches. We report a case of a 51-year-old female with slow-growing skin-colored nodules over the tip of the nose and left nasal ala, with characteristic histopathological features suggestive of trichoadenoma.Publication A Comparative Efficacy and Adverse Clinical Events of Methotrexate versus Azathioprine with Steroid Mini Pulse Therapy in the Management of Moderate to Severe Alopecia Areata: A Tertiary Centre Based Interventional Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Mishra, Aditi; KC, Shekhar; Shrestha, Elisha; Pandey, Chandranshu; Karn, DharmendraAbstract: Introduction: Alopecia areata is a T cell-mediated autoimmune disorder of hair follicles resulting in partial or total hair loss. Treatment of alopecia areata is difficult, and it has variable severity. Objectives: To compare the clinical efficacy and adverse clinical events of azathioprine versus methotrexate with steroid minipulse therapy in managing moderate to severe alopecia areata. Materials and Methods: Prospective non-blinded clinical trial conducted for 6 months in Department of Dermatology at Dhulikhel Hospital. Dermoscopic evidence of alopecia areata patients treated according to group assigned and effects and adverse event were noted. Results: There was a total of 36 patients enrolled. Twenty patients were in Group A (AZT+MPT) and 16 in group B (MTX+MPT). There was a significant improvement in SALT score at 6 months (Group A p-value: 0.03; group B p-value: 0.001). Treatment efficacy (percent scalp hair regrowth) in group A was 79.2%, and in group B was 89.01%. Conclusion: Both treatment regimens showed marked improvement with SALT score reduction; however, methotrexate with steroid minipulse therapy showed slightly higher treatment efficacy than azathioprine with steroid minipulse therapy.