Browsing by Author "Thapa, Deeptara Pathak"
Now showing 1 - 19 of 19
Results Per Page
Sort Options
Publication A Neglected Swollen Limb: Resurgence or Common Tropical Disease?(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Ray, Sumit; Thapa, Deeptara PathakAbstract: Mycetoma is uncommon, chronic granulomatous infection caused either by fungi or by aerobic filamentous actinomycetes which is characterized by a triad of painless subcutaneous mass, multiple sinuses and discharge containing grains. We report a case of 40 years old male, farmer who presented with multiple painless swollen lesions over right foot for 8 years. Swelling had gradually increased in size over a few years followed by multiple episodes of discharge. It had not restricted his daily activities. On examination, there were multiple nodules and sinuses discharging serous fluid from the right foot. Gram staining showed gram positive filamentous rods and KOH was negative. Histopathology showed multiple granulomas. Patient was treated for 5 cycles using modified Welsh regimen with Amikacin 750mg intravenously once a day, oral Cotrimoxazole 960mg twice daily and oral Rifampicin 600mg once daily along with oral iron and folic acid supplementation continuously for 21days which constituted 1 cycle with an interval of 15 days between each cycle. Patient was assessed by measuring girth of foot and number of lesions in each visit and showed significant improvement at the end of fifth cycle. Patient was followed for 1 year after treatment without any recurrence.Publication A Sinister Disease Hides Behind Recalcitrant Mucocutaneous Disorder(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2021) Adhikari, Harihar; Thapa, Deeptara Pathak; Bhusal, PriyaAbstract: Paraneoplastic pemphigus (PNP) is a rare autoimmune disorder associated with underlying benign or malignant neoplasia. Its signs and symptoms may be the first presentation of a concealed malignancy. Due to late diagnosis, prognosis of PNP is not good, so early diagnosis and treatment is of paramount importance. We present a case of 22 years old female who presented to our out patient department (OPD) with history of recurrent, severe, recalcitrant, painful oral ulcers; lichenoid lesions over the hands and feet and widespread blistering and erosions involving the soles. Histopathological examination was consistent with paraneoplastic pemphigus and showed features of lichenoid dermatitis. CT scan revealed retroperitoneal mass suggestive of Castleman disease. The patient was referred to surgical team for further management.Publication Aesthetic Dermatology Training During Residency: Do we Need to Revise the Postgraduate Curriculum?(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Marahatta, Suchana; Thapa, Deeptara PathakAbstract: Aesthetic Dermatology (AD) is a growing sub-unit of dermatology. Appearance plays a vital role in enhancing and boosting self-confidence. Reports are showing a growing demand for AD throughout the world. To converge this increasing demand, we must pivot on engendering certified competent dermatologists and hence include this sub-specialty in the dermatology residency program.Publication Aesthetic Dermatology, The Rising Trend(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Keyal, Uma; Thapa, Deeptara PathakAbstract: Aesthetic Dermatology, also known as cosmetic dermatology provides treatment for skin, hair or body that emphasizes on improving an individual’s appearance. It is widely conducted to treat conditions such as moles, wrinkles, scars, excess fat, skin discoloration, skin laxity, and cellulite. Benefits such as minimally invasive or non-invasive and relatively less time-consumption with better outcomes has foster the patients to seek these treatments. With soaring demand for these treatments, numerous myths and misconceptions regarding the field of aesthetic dermatology have arisen which need to addressed. Also, this constantly evolving field with new devices and tools requires extra vigilance, continue medical education and a governing body to have check upon negligent professional activity, if occurs anyPublication Awareness and Pattern of Sexually Transmitted Diseases: A Hospital Based Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Thapa, Deeptara Pathak; Rana, ArnijaAbstract: Introduction: Sexually transmitted diseases (STDs) are infections that occurs due to sexual contact. There are various pathogens contributing for STDs. There is a rising trend of STDs globally, but actual reported cases are low due to low screening and reporting. Materials and Methods: This study was a prospective hospital-based study. Patients were included in the study according to the inclusion criteria. All data were recorded in a preset proforma. Routine laboratory investigations along with STD workup was done in patients. Results: A total of 62 patients were included in the study according to the inclusion criteria. The age ranged from 17-52years. There were 63% males and 37% females. The majority of patients were employed (60%). Regarding awareness about symptoms of STDs, the patients responded as Infertility in 22%, ulcers in 17%, followed by swelling, genital discharge, dyspareunia, and 24% gave multiple response. Regarding attitude about awareness of prevention of STDs, maximum patients (43%) responded that, through condom use, prevention of the STDs was possible. Out of the total patients 58% Spouse were the commonest partner in 27%. The patients presented with symptoms like urethral discharge in 26%, followed by genital ulcers, genital growth, mixed infections and vaginal discharge. The commonest diagnosis was Syphilis followed by Gonococcal urethritis, non-gonococcal urethritis, warts, Genital herpes, vulvovaginal candidiasis, molluscum contagiosum, and mixed infections. Conclusion: Syphilis is the most prevalent STD, according to the current study. Due to the dearth of knowledge regarding STDs, the STD patients, who visit our facility may only be the tip of the iceberg. It is necessary to spread awareness about STDs among individuals through social media and educational institutions, starting at the local level and moving up to the national level.Publication Book Review - Dermoscopy Atlas of Facial Melanoses(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Thapa, Deeptara PathakAbstract: Handbook of Facial Melanosis by Dr Bibush Amatya is an excellent book worth reading and seems well mounted for post graduate medical students, young Dermatologists and senior consultants alike, who want to improvise their practice with Dermoscopy.Publication Clinico-epidemiological Profile and Photoprotective Behaviour among Patients with Photodermatosis: A Hospital-based Cross-sectional Study(Institute of Medicine, Tribhuvan University, 2025) Bhusal, Mohan; Dhungana, Sanjay; Rana, Arnija; Shrestha, Shristi; Thapa, Deeptara Pathak; Piya, SmritiAbstract: Introduction Photodermatoses (PD) encompass a spectrum of skin conditions induced or exacerbated by sunlight. There is limited data on their clinico-epidemiological profile in Nepal. This study aimed to assess the prevalence and study the clinic-epidemiological profile and photoprotective behaviour among patients with photodermatoses. Methods This hospital-based descriptive cross-sectional study was conducted between September 2023 to August 2024 in the outpatient department of dermatology of a tertiary care centre. Ethical approval was obtained from the Institutional Review Committee. The number of patients diagnosed with PD were determined using Sukraa Hospital Information Management System software, V1.2.24.5 for the calculation of prevalence. Non-probability convenience sampling was used. A total of 69 patients clinically diagnosed with photodermatoses were included in study. Data were collected using a structured proforma and analyzed using Statistical Package for Social Sciences (SPSS) version 16. Results Prevalence of photodermatitis was 2.24% (338/15116). Polymorphic light eruption was the most common diagnosis 48 (69.57%), followed by photo-contact dermatitis. The prevalence was higher among females 41 (59.42%), with a mean age of 37.21±18.18 years. Most patients were in the 21–30 years age group. The neck 28 (28.28%) and face 20 (20.20%) were the most commonly affected sites, and papules were the predominant lesion morphology 41(42.27%). Only 15 (21.74%) used photoprotective measures, of which sunscreen was the most common 10 (66.67%). Conclusion Polymorphic light eruption was the most common type of photodermatosis, particularly among females and younger individuals. There was a notably low use of photoprotective measures among patients with PD, particularly sunscreen usage.Publication COVID-19 and Dermatologist: A Scenario from Nepal(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2021) Thapa, Deeptara Pathak; Paudel, VikashAbstract: Corona virus disease-2019 (COVID-19) had impacted the healthcare sector severely. The impact of pandemic had a foothold even on dermatology practice and dermatology residency teaching programs. Patients with dermatological diseases, few diseases arising due to COVID-19 and patients with immunosuppressive for chronic dermatological conditions were affected. In the midst of this pandemic, all dermatologist should learn and contribute to the mankind with precaution at all level either in healthcare or society.Publication Cutaneous Reactions Following Anticancer Drug Therapy in a Tertiary Care Centre(Nepal Medical Association, 2024) Thapa, Deeptara Pathak; Shrestha, Sudip; Shrestha, SaloniAbstract Introduction: Cutaneous reactions are dermatological abnormalities that can occur after anticancer drug therapy in cancer patients. Cutaneous reactions can range from mild dermatological disorders to life-threatening medical conditions and may worsen a patient's quality of life. This study aimed to find out the prevalence of cutaneous reactions following anticancer drug therapy in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among cancer patients following anticancer therapy in the outpatient department of dermatology of a tertiary care centre between 1 October 2021 to 30 December 2022. Convenience sampling was done. The point estimate was calculated at a 95% Confidence Interval. Results: Among 3,288 patients, the prevalence of cutaneous reactions following anticancer drug therapy was seen in 73 (2.22%) cancer patients. The mean age was found to be 49.42±1.45 years. Anagen effluvium was the frequently observed cutaneous reaction (30.10%) followed by palmar-plantar erythrodysesthesia (19.94%). Conclusions: The prevalence of cutaneous reactions following anticancer drug therapy among cancer patients was found to be lower as compared to the studies conducted in similar settings. An interdisciplinary approach is required to identify cutaneous reactions to anticancer therapy and to navigate change in the treatment plan.Publication Dermoscopy of Non-Melanocytic Skin Tumors: A Descriptive Study in a Tertiary Care Hospital(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Thapa, Deeptara Pathak; Bhandari, Sajana; Adhikari, Harihar; Joshi, SammiAbstract: Introduction: Dermoscopy is a non-invasive technique that enhances visualization of morphological lesions invisible to naked eye examination and aids in clinical diagnosis. We study its role in non-melanocytic skin tumors. Objectives: The purpose of this study was to evaluate and compare the dermoscopic features of non-melanocyte skin tumors of skin Materials and Methods: A cross-sectional hospital-based study including patients clinically diagnosed as non-melanocytic epidermal tumors was conducted. All dermoscopic findings were studied using a handheld pocket dermoscope (Dermlite DL1) and recorded in a preset proforma. Results: A total of 100 patients were enrolled in the study with mean age of 37 (+/-18.34). There were 56 % females. The face was the commonest site of involvement (56%). Seborrheic keratosis was the commonest clinical diagnosis (55%), followed by pyogenic granuloma 8%, cherry angioma 7%, haemangioma 6%, basal cell carcinoma 5%, achrochordons 4%, xanthelasma, and sebaceous hyperplasia in 3% each. Squamous cell carcinoma and actinic keratosis were seen in 2% each; Angiokeratoma, Bowens disease, stetocytoma multiplex, syringoma, and neurofibroma were all found in 1% of the patients. In dermoscopy, vascular changes were seen in 41% patients, which appeared as regular in 56.1% and rest 43.9% as irregular. Non-vascular changes were seen in 68%. Dermoscopic findings of vascular and non-vascular changes were statistically significantly associated with various types of non-melanocytic epidermal tumors (P <0.05). Conclusion: Our study shows histopathological correlation with the existing dermoscopic characteristics increases the diagnostic accuracy of various non-melanocytic tumors. However, more studies are warranted to statistically prove its utility.Publication Dermoscopy of Psoriasis: A Cross Sectional Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Thapa, Deeptara Pathak; Adhikari, Harihar; Bhandari, SajanaAbstract: Introduction: Dermoscopy is a non-invasive tool that aids in the diagnosis of dermatological diseases. Objectives: The study aims to evaluate the dermoscopic features of psoriasis in the skin. Materials and Methods: All patients clinically diagnosed with psoriasis were enrolled in the study. Dermoscopic findings were studied using a handheld pocket dermoscope (Dermlite DL1) with high magnification. Dermoscopic examination used both polarizing and non-polarizing lenses. Results: The age of the patients ranged from 12 years to 58 years, and the mean age of presentation was 30 years (+/-12.7 years). There were 52% females and 48% males. In dermoscopy, vascular changes were seen in 90%. Vessel arrangement was seen as uniform in 80% of the cases and non-uniform in 20%. Dotted vessels were seen in 88%, glomerular and comma-shaped vessels in 2%. In 94%, white scales were seen, followed by yellow scales in 2% and mixed types in 4%. The background color was red in 68% of cases, pink in 26%, and brownish in 6%. Pigmentary changes were observed in 16%. Follicular changes were observed in 6%. Conclusion: The present study analyzed the characteristic of dermoscopic features in psoriasis. Further studies should be conducted, including inflammatory disorders and their correlation with dermoscopic features.Publication Graham-Little-Piccardi-Lassueur Syndrome: Two Case Reports(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2024) Piya, Smriti; Bhusal, Mohan; Thapa, Deeptara Pathak; Shrestha, JoshanaAbstract: Graham-Little-Piccardi-Lassueur Syndrome (GLPLS) is a rare lichen planopilaris (LPP) subtype associated with scarring alopecia. It is thought to be an immune-mediated cause of alopecia. It is characterized by a triad of multifocal cicatricial alopecia of the scalp, noncicatricial alopecia of the axilla, and groin and a follicular lichen planus (LP) eruption. Herein, we present 2 cases of GLPLS. The first case is of a 33-year-old female presented with classical lichen planopilaris (LPP) of the scalp, follicular hyperkeratosis of bilateral arms, and noncicatricial alopecia of armpits. In the second case, a 17-year-old female presents with frontal fibrosing alopecia (FFA) of the scalp, follicular hyperkeratotic papules of the scalp, and noncicatricial alopecia of the bilateral armpits and genitalia. The physician can miss GLPLS due to the rarity of the condition.Publication Helicobacter Pylori Infection Induced Henoch Schonlein Purpura: A Case Report(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Bhandari, Sajana; Thapa, Deeptara PathakAbstract: Henoch Schonlein Purpura (HSP) also known as IgA vasculitis, is an immune complex vasculitis affecting small vessels. We report a case of 53 years old female who presented with multiple reddish-brown purpuric papules over bilateral lower limb for 10 days. Her cutaneous findings were suggestive of HSP. She also had a history of recurrent dyspepsia for the past 6 months for which she had been taking antacid from a local pharmacy infrequently. To confirm her diagnosis, skin biopsy was sent for both histopathological examination and direct immunofluorescence which were suggestive of HSP. We referred her to the medicine department for her gastrointestinal complaints where upper gastrointestinal endoscopy was performed and the finding was consistent with Helicobacter pylori (H. pylori) infection. The patient was started on a treatment regimen for H. pylori eradication which resulted in a dramatic improvement in both gastrointestinal complaints as well as cutaneous lesions. There are very few cases in the literature showing an association between HSP and H. pylori infection and none from our part of the world.Publication Is Aesthetic Dermatology in Unsafe Hands? Authors(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2023) Bhusal, Mohan; Thapa, Deeptara PathakAbstract: Aesthetic Dermatology is one of the growing subspecialities that involves noninvasive to minimally invasive cosmetic procedures. It has overlapping scope with Aestheticians, Beauticians, and Non-Dermatologist medical practitioners, adding ambiguity and ethical issues. There have been global reports of invasive procedures done by Beauticians and Aestheticians leading to complications like scalp burn, infection and stroke which later led to development of guidelines in different countries. There is a strong need to develop similar guidelines in Nepal in collaboration with different stakeholders. Also, it is equally important to create public awareness so that public will be better informed about whom to consult for their skin concerns, and if needed report to governing bodies regarding negligence.Publication Mycosis Fungoides: A Case Report(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2021) Joshi, Anisha; Thapa, Deeptara PathakAbstract: Mycosis fungoides is the most common primary cutaneous T-cell lymphoma and is recognized as one of the rare malignant skin neoplasms. Hypopigmented mycosis fungoides is a variant of mycosis fungoides, described in dark-skinned individual and Asian patients. We report a case of 32 years old Nepalese female who had presented with multiple asymptomatic hypopigmented macules over the bilateral arms, thighs, abdomen, back of trunk and buttocks. Skin biopsy revealed few atypical cells (small/medium-sized, cerebriform nuclei with halo) confined to epidermis with epidermotropism. Immunohistochemistry showed CD3, CD4, CD5 and CD8 positivity. The patient was managed with topical steroids, oral methotrexate and phototherapy, and she is on regular follow up. As the disease has an indolent clinical course, long term follow up is necessary. Keywords: Histopathology, Immunohistochemistry, Mycosis FungoidesPublication Quality of life in Patients with Melasma: A Hospital-Based Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Mainali, Priyanka; Jha, Anil Kumar; Shrestha, Shristi; Thapa, Deeptara Pathak; Joshi, Smita; Amatya, BibushAbstract: Introduction: Melasma is the most common cause of facial melanosis and one of the most common diseases presenting to the Dermatology department. It can lead to psychological and emotional distress for the patients and can hamper their quality of life. So, this study was done to assess the quality of life among patients with melasma so that the need for couseling of these patients could be assessed along with medical treatment. Materials and Methods: This was a hospital based cross sectional study with 205 clinically diagnosed cases of melasma during the study period of one year. Melasma area severity index (MASI) score was recorded for each patient. Melasma quality of life was evaluated using the Melasma related Quality of Life (MELASQOL) score. MASI score and MELASQOL score were correlated using the Chi square test and socio-demographic details were also recorded. Results: The mean MASI score in our study was 14.39 and the mean MELASQOL score was 34.98. The correlation of the MASI score with the MELASQOL score was found to be statistically significant (p value = 0.000). Conclusion: MELASQOL score can be used to assess the quality of life in patients with melasma and the impairment in quality of life depends upon the MASI score.Publication Rare Solitary Naevus Lipomatosis Cutaneous Superficialis: Histopathology A Diagnostic Clue(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2021) Thapa, Deeptara Pathak; Singh, MoushamiAbstract: We present a case of 45 year old female, presenting with a solitary, asymptomatic, pedunculated mass since childhood. The lesion was totally excised and was sent for histopathological evaluation and was found to be Naevus lipomatosis cutaneous superficialis which is a rare form of hamartoma in which mature adipocytes are found in the dermis. Keywords: Adipocytes, Hamartoma, NevusPublication Standardizing Editorial Process Towards Quality(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Thapa, Deeptara Pathak; Pradhan, SushmitaAbstract: A quality journal depends upon well-organized, structured, and efficient editorial activity. In addition, it is also determined by robust peer-review, pellucid focus and scope of the journal, amiability to authors, and open access for scholarly exchange of scientific research for paramount researchers worldwide.Publication Trichoscopic Study on Tinea Capitis: A Hospital Based Study(Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON), 2022) Joshi, Anisha; Jha, Anil Kumar; Shrestha, Shristi; Thapa, Deeptara Pathak; Joshi, Smita; Amatya, BibushAbstract: Introduction: Tinea capitis is a common dermatophyte infection of the scalp and hair shaft, most commonly observed in children. Trichoscopy is nonivasive tool which helps in early diagnosis and prompt treatment of tinea capitis. Objectives: This study was carried out with the aim to describe the trichoscopic features of tinea capitis and to find out its different clinical variants with the aid of trichoscopy. Materials and Methods: This is a hospital based cross sectional descriptive study conducted from 1st January 2019 to 31st December 2019. All patients clinically diagnosed with tinea capitis were included in the study. Result: A total of 50 patients with tinea capitis were recruited. The most common age group was found to be 6-10 years (52%) and 27 patients (54%) were female. Majority of the population were students, i.e. 46 patients (92 %). Family history was positive in 38% of cases. The clinical variants seen were black dots in 20 patients (40%), followed by gray patch in 15 patients (30%), kerion in 8 patients (16%) and combined type (both gray patch and black dots) in 4 patients (8%). The most common trichoscopic feature were black dots in 40 (80%), followed by comma hairs in 38 (76%), corkscrew hairs in 33 (66%), and broken hairs in 24 (48%). Conclusion: This study highlighted that the use of trichoscopy as non-invasive tool helped in diagnosing the cases of tinea capitis without the use of wood’s lamp and laboratory investigations.