Publication: Mycosis Fungoides: A Case Report
Files
Date
2021
Authors
Article Type
Case Report
Journal Title
Journal ISSN
ISSN 2091-0231 eISSN 2091-167X
Volume Title
Pages
Pages: 60 - 64
Publisher
Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
Abstract
Abstract:
Mycosis fungoides is the most common primary cutaneous T-cell lymphoma and is recognized as one of the rare malignant skin neoplasms. Hypopigmented mycosis fungoides is a variant of mycosis fungoides, described in dark-skinned individual and Asian patients. We report a case of 32 years old Nepalese female who had presented with multiple asymptomatic hypopigmented macules over the bilateral arms, thighs, abdomen, back of trunk and buttocks. Skin biopsy revealed few atypical cells (small/medium-sized, cerebriform nuclei with halo) confined to epidermis with epidermotropism. Immunohistochemistry showed CD3, CD4, CD5 and CD8 positivity. The patient was managed with topical steroids, oral methotrexate and phototherapy, and she is on regular follow up. As the disease has an indolent clinical course, long term follow up is necessary.
Keywords: Histopathology, Immunohistochemistry, Mycosis Fungoides
Description
Anisha Joshi
Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal
https://orcid.org/0000-0001-8316-3259
Deeptara Pathak Thapa
Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal
Keywords
Identifier
https://doi.org/10.3126/njdvl.v19i1.34167