Browsing by Author "Thapaliya, Sabin"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Publication Pharmacotherapy of Hospitalized Patients with COVID-19 at a Tertiary Care Hospital in Nepal(Institute of Medicine, Tribhuvan University, 2025) Mudvari, Anish; Prasad, Pravin; Pokharel, Akritee; Thapaliya, Sabin; Maharjan, Bindira; Khadka, Rebanta; Lamsal, Arun Batsa; Ghimire, Ranjeet; Bista, ApekshaABSTRACT: Introduction The COVID-19 pandemic poses a major health threat with no standardized treatments for SARS-CoV-2. This study evaluates pharmacotherapy trends in COVID-19 patients during the second wave at a tertiary care facility. Methods A retrospective, observational, cross-sectional study was conducted in a tertiary care centre, utilising patient data from April 2021 to July 2021. The sample included 310 patients admitted with a confirmed diagnosis of COVID-19. Patients were classified based on oxygen requirement levels, and data were analysed using descriptive statistics. Results Of the 310 patients, 59% were male and 41% female, with a mean age of 53.37 ± 17.01 years. The average hospital stay was 10 ± 7.15 days. Most patients (66.8%) required supplemental oxygen, and 7.4% required mechanical ventilation. The majority received antibacterial therapy (307, 99.03%), with ceftriaxone being the most commonly prescribed antibiotic (73.22%). Remdesivir was the predominant antiviral, and dexamethasone was used in 88.39% of patients. Conclusion Antibiotic use was extensive among hospitalised COVID-19 patients, with ceftriaxone being the most common. Antiviral use was less frequent, with Remdesivir being the preferred choice. Dexamethasone played a crucial role in managing severe cases.Publication Ulcerative Colitis with Superior Sagittal Sinus Thrombosis: A Case Report(Nepal Medical Association, 2023) Basnet, Somika; Bhandari, Abashesh; Basnet, Bhupendra Kumar; Thapaliya, SabinAbstract Ulcerative colitis is a chronic inflammatory, idiopathic, condition of the mucosa of the colon. Cerebral venous thrombosis is one of the serious and rare complications of inflammatory bowel disease. We report a case of a 27-year-old female patient with complaints of loose stool 5 to 6 episodes per day mixed with blood for 10 days. The patient has severe per rectal bleed, not controlled despite adequate measures and a few days later developed altered sensorium and fits. This case highlights prompt diagnosis and early treatment managing both severe ulcerative colitis and sagittal venous thrombosis. Immediate recognition of her disease improved her condition drastically and increased her survival.