Journal Issue:
Volume: 15, No 3, Issue 59, JULY-SEPT, 2017

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Volume

Number

Issue Date

2017

Journal Title

Journal ISSN

1812-2027

Journal Volume

Journal Volume
Volume: 15

Articles

Publication
Diet and Health – What Should We Eat ?
(Kathmandu University, 2017) Shrestha, Archana; Spiegelman, Donna
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Publication
Role of Endoscopic Modified Inlay Butterfly Cartilage Perichondrium Myringoplasty in Hearing Outcome and Graft Uptake
(Kathmandu University, 2017) Shrestha, BL; Dhakal, A; Pradhan, A; Rajbhandari, P
ABSTRACT Background The endoscopes have better optics and magnification with wide angle of view due to angled lenses. It provides the excellent resolution of image in surgeries having many difficult anatomic nooks and corners like; antero-inferior recess of external auditory canal, middle ear cavity and difficult areas to visualize under microspore like sinus tympani. Likewise, the use of cartilage has very low metabolic rate, provide support to prevent retraction and reacts minimally to inflammatory reaction, so it has advantageous role in closure of tympanic membrane perforations. Objective The main objective of our study is to see the graft uptake rate and hearing results after endoscopic cartilage myringoplasty with our own modification. Method This is a prospective, cohort study conducted among 37 patients who underwent endoscopic modified inlay butterfly cartilage perichondrium myringoplasty using tragal cartilage. The hearing was assessed by comparing pre with post-operative ABG (Air bone gap) and ABG closure in speech frequencies (500Hz, 1KHz, 2KHz, 4KHz). Result Among 42 patients, 37 (88.09%) had graft uptaken. Other five patients had residual perforation because of infection. The post-operative ABG was smaller than pre- operative ABG.(26.41±8.47dB and 36.57±12.13dB respectively). The mean ABG closure was 10.15±10.23dB. The ABG closure was ≤ 10dB in 28(75.6%) patients. Conclusion Endoscopic modified inlay butterfly cartilage perichondrium myringoplasty has advantages in terms of hearing results and graft uptake rate as it is comparable or even better than others. So, it is advisable to perform this technique without any difficulty. KEY WORDS Air bone gap, cartilage, endoscope, myringoplasty
Publication
Comparative Study to Determine the efficacy of Zinc Oxide Eugenol and Alveogyl in Treatment of Dry Socket
(Kathmandu University, 2017) Chaurasia, NK; Upadhyaya, C; Dixit, S
ABSTRACT Background Dry socket is one of the most common complications following permanent tooth extraction, especially mandibular third molar. Management remains controversial and different authors have shown different results with the use of zinc oxide eugenol and AlveogylTM, some preferring AlveogylTM over zinc oxide eugenol. Objective To determine the incidence, possible risk factors and compare the effectiveness of two most commonly used agents (Zinc oxide eugenol and AlveogylTM) for management of dry socket. Method Dry socket patients were randomly divided into two groups. Various risk factors were recorded through proper history. After thorough irrigation with normal saline, zinc oxide eugenol paste mixed with cotton pellet was placed in one group whereas AlveogylTM was placed in another group. Intensity of pain was recorded on visual analogue scale of Zero to ten. Pain score was recorded at the time of diagnosis, thirty and sixty minutes after placement of medication and on second, fifth, seventh and tenth day. The medication was changed every day until the pain subsided. The data were collected and analyzed using SPPS software (version 20). Result Incidence of dry socket was 4.70%, more common in males (59.09%). It was more common after extraction mandibular third molar. Initial and final pain relief on visual analogue scale was better with use of zinc oxide eugenol. Conclusion Zinc oxide Eugenol paste is more effective in management of dry socket for early as well as final pain relief compared to AlveogylTM. KEY WORDS Alveogyl, dry socket, visual analogue scale, zinc oxide eugenol
Publication
Intramedullary Nailing System in Unstable Both Bone Diaphyseal Fractures in Children
(Kathmandu University, 2017) KC, BB; Lamichhane, N; Parajuli, SP; Maharjan, S
ABSTRACT Background Forearm fractures in pediatric population is usually managed conservatively. Unstable fractures need operative intervention like closed or open intramedullary nailing or open reduction and internal fixation with plates and screws. However, there is no consensus regarding the method of treatment according to age group. Objective To standardize the use of elastic nailing system as effective form of treatment in terms of function, cost and lower complications as compared to widely used titanium nails in developed countries. Method Sixty eight pediatric patients with both bone forearm diaphyseal fractures were managed with closed reduction and intramedullary fixation with rush nail or k-wire and followed at least for 6 months for evaluation of radiological and functional outcome. Result Patients were divided into two age groups, Group A for age of 5 to 9 years (26 patients) and Group B for age of 10-15 years (42 patients). The mean time for union for Group A patient was 7.31 weeks which was significantly lower than that of Group B patients of 9.33 weeks (p-value <0.05). All the patients in Group A had excellent outcome and 36 (85.7%) patients had excellent outcome and 6 (14.3%) had good outcome in Group B. 5 out of 68 cases (7.35 %) had minor complications (2 in Group A and 3 in Group B). The mean time for implant removal was 17.9 weeks in Group A and 22.9 in Group B. Conclusion Intramedullary fixation for unstable diaphyseal both bone fractures of forearm is safe and cost effective method of treatment with good to excellent functional outcome with union time being significantly lower in younger age group. KEY WORDS Children, diaphyseal forearm fracture, intramedullary nail
Publication
Prevalence of Diastolic Dysfunction in Type 2 Diabetes Mellitus
(Kathmandu University, 2017) Yadava, SK; Dolma, N; Lamichhane, G; Poudel, N; Barakoti, M; Karki, DB
ABSTRACT Background Diastolic dysfunction is an inability of the ventricle to fill to a normal end-diastolic volume, both during exercise as well as at rest. Diabetes mellitus increases the risk of heart failure even in the absence of other co-morbidities. Objective To find the prevalence of diastolic dysfunction in patients with type 2 diabetes mellitus and its association with age, gender, duration, glycosylated hemoglobin levels, dyslipidemia, tobacco smoking and alcohol consumption. Method Ninety patients with type 2 diabetes mellitus of both genders, aged 30 to 60 years, were included in this study. Doppler echocardiography was performed to evaluate diastolic dysfunction. Result The mean age of the study population was 46.21 ± 9.20 yrs. The overall prevalence of diastolic dysfunction in the study population was 47.8%. The prevalence of diastolic dysfunction increases with age: 23.1% in patients of age 30 – 39 yrs to 65.8% in patients of age 50 – 60 yrs (adjusted OR 0.16, 95% CI 0.04 - 0.64, P = 0.010) and with the duration of diabetes: 32.8% in patients with diabetes for <5 yrs to 75% in patients with diabetes for >10 yrs (adjusted OR 0.31, 95% CI 0.08 - 1.00, P = 0.05). There was no significant association between diastolic dysfunction and dyslipidaemia, BMI, tobacco smoking, alcohol consumption, HbA1c and gender. Conclusion Prevalence of diastolic dysfunction in type 2 diabetes mellitus was 47.8% in our study. A rising trend of prevalence of diastolic dysfunction with the duration of diabetes and increasing age of patients was observed. KEY WORDS Diastolic dysfunction, Prevalence, Type 2 diabetes mellitus

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