Publication:
Thyroid Disorders in Patients with Polycystic Ovarian Syndrome in a Tertiary Care Center: An Observational study

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorSharma, Jyotshna
dc.contributor.authorMahat, Bimita
dc.contributor.authorTiwari, Sanjeeb
dc.contributor.authorSingh, Niraj Kumar
dc.contributor.authorThapa, Durga
dc.contributor.authorYadav, Ranjana
dc.date.accessioned2025-07-30T07:04:24Z
dc.date.available2025-07-30T07:04:24Z
dc.date.issued2024
dc.descriptionJyotshna Sharma Department of Obstetrics and Gynaecology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal Bimita Mahat Department of Obstetrics and Gynaecology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal Sanjeeb Tiwari Department of General Practice, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Niraj Kumar Singh Department of Internal Medicine, Narayani Hospital, Birgunj, Parsa, Nepal Durga Thapa Department of Obstetrics and Gynaecology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal Ranjana Yadav Department of Obstetrics and Gynaecology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal
dc.description.abstractAbstract Introduction: Polycystic ovarian syndrome is the most common endocrine and metabolic disorder in women of childbearing age, affecting 3–15% of women worldwide, leading to reproductive, metabolic, and psychological issues. Patients with polycystic ovarian syndrome require rigorous thyroid function detection, monitoring, and correction over time. In this study, we aimed to evaluate the clinical presentations and thyroid dysfunction in patients with polycystic ovarian syndrome. Methods: An observational study was done in patients with polycystic ovarian disease presenting to a tertiary care centre over six months, from December 2023 to May 2024 Total population sampling was done. All the women during the study period diagnosed with polycystic ovarian disease based on Rotterdam criteria were included in the study after getting ethical approval from the institutional review board. (Reference number: 20102023/03). Results: The mean age of women in the study was 24.74±5.01 years. A total of 28 (31.46%) patients of polycystic ovarian disease had hyperthyriodism, hypothyroidism was found in 13 (14.60%) and subclinical hypothyroidism was found in 6 (6.74%) patients. All the women had menstrual irregularities. Regarding androgenic characteristics, 53 (59.55%) of patients presented with hirsutism, 43 (48.51%) presented with acne, 13 (14.61%) women had alopecia, and 4 (4.49%) women had acanthosis. Conclusions: Hyperthyroidism, hypothyroidism and subclinical hypothyroidism were prevalent in polycystic ovarian disease patients, emphasizing the need for thorough thyroid evaluation in polycystic ovarian disease patients due to its impact on metabolic and reproductive health. High rates of menstrual irregularities, androgenic symptoms like hirsutism and acne, and fertility challenges were also prevalent, aligning with findings from similar studies.
dc.identifierhttps://doi.org/10.31729/jnma.8833
dc.identifier.urihttps://hdl.handle.net/20.500.14572/961
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.titleThyroid Disorders in Patients with Polycystic Ovarian Syndrome in a Tertiary Care Center: An Observational study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage822
oaire.citation.startPage819
relation.isJournalIssueOfPublicationf18dd8cc-69b0-42e7-9684-ccae5c5bd0df
relation.isJournalIssueOfPublication.latestForDiscoveryf18dd8cc-69b0-42e7-9684-ccae5c5bd0df
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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