Publication: Benign Recurrent Aseptic Meningitis (Mollaret’s Meningitis) in an Elderly Male: A Case Report
Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Mollaret’s meningitis is an aseptic recurrent benign lymphocytic meningitis lasting 2-5 days and occurs over years with spontaneous complete resolution of symptoms between episodes. An 88 years-old-male presented with acute onset headache, lethargy and altered sensorium after a recent ear infection. He had multiple similar episodes in the past, each preceded by ear or sinus infection with cerebrospinal fluid finding consistent with aseptic meningitis. However, no specific causative agent was ever identified. He was confused, disoriented and lethargic with normal vitals and systemic examination. Blood tests showed leukocytosis with neutrophilia. Cerebrospinal fluid analysis revealed increased cell count with lymphocyte predominance, elevated protein and negative polymerase chain reaction. Magnetic resonance imaging of brain showed chronic small vessel ischemic changes. He fulfilled the Bruyn’s criteria for clinical diagnosis. He was empirically administered acyclovir during hospitalization and was discharged without prophylactic antiviral
due to negative cerebrospinal fluid analysis, culture, and multiplex polymerase chain reaction.
Description
i Chand
Department of Internal Medicine, Rochester General Hospital, Rochester, USA
Sangharsha Thapa
Kathmandu University School of Medical Sciences, Dhulikhel, Kavrepalanchowk, Nepal
Khusal Gautam
Department of Pediatric Research, Patan Academy of Health Sciences, Lalitpur, Nepal
Anu Radha Twayana
Kathmandu University School of Medical Sciences, Dhulikhel, Kavrepalanchowk, Nepal
https://orcid.org/0000-0001-7399-5043
Maryrose R.Laguio-Vila
Department of Internal Medicine, Rochester General Hospital, Rochester, USA
Tarek Elshourbagy
Faculty of Medicine, Cairo University, Egypt
Keywords
aseptic meningitis, benign recurrent, Mollaret's meningitis