Publication: Rapid detection of helicobacter pylori by endoscopic brush cytology and comparison with histopathology
Date
2007
Authors
Article Type
Original Article
Journal Title
Journal ISSN
1812-2027
Volume Title
Pages
Pages: 387 - 390
Publisher
Kathmandu University
Abstract
Objectives: The main objective of this study was to assess antral brush cytology as an alternate approach for the
diagnosis of H. pylori infection as compared to histopathology.
Methods: 75 cases with diagnosis of antral gastritis underwent endoscopic antral biopsy as well as antral brushing
cytology was included irrespective of age and sex. Cytological slides were stained with Giemsa stain & biopsy
slides were stained with H&E and Giemsa stain. Correlation was done between cytological smear slides and biopsy
slides.
Results: Among 75 cases, H. pylori were positive in 55 (73.4%) cases of biopsy specimens while in brush cytology
it was positive in 48 (64%) cases. In 45 (60%) of 75 cases, H. pylori was seen in both biopsy and brush cytology.
Conclusion: Endoscopic brush cytology provides an accurate, inexpensive and easy technique in the rapid detection
of H.pylori infection.
Key words: Brush cytology, H.pylori
Description
Akhter J 1 , Shrestha HG2
1Lecturer, Department of Pathology, KMCTH,
2Professor and HoD, Department of Pathology, NMCTH