Article:
Acute coronary syndrome in an intensive care unit of a tertiary care centre: the spectrum and coronary risk factors

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorGautam, Mani Prasad
dc.contributor.authorSogunuru, Guruprasad
dc.contributor.authorSubramanyam, Gangapatnam
dc.contributor.authorThapa, Lekhjung
dc.contributor.authorPaudel, Raju
dc.contributor.authorGhimire, Madhav
dc.contributor.authorGautam, Samir
dc.contributor.authorGhimire, Usha
dc.contributor.authorShilpakar, Ramila
dc.creator.affiliationDepartment of Cardiology, College of Medical Sciences, Bharatpur, Nepal.
dc.creator.affiliationDepartment of Cardiology, College of Medical Sciences, Bharatpur, Nepal.
dc.creator.affiliationDepartment of Cardiology, College of Medical Sciences, Bharatpur, Nepal.
dc.creator.affiliationDepartment of Cardiology, College of Medical Sciences, Bharatpur, Nepal.
dc.creator.affiliationDepartment of Neurology, College of Medical Sciences, Bharatpur, Nepal.
dc.creator.affiliationDepartment of Nephrology, College of Medical Sciences, Bharatpur, Nepal.
dc.creator.affiliationDepartment of Nephrology, College of Medical Sciences, Bharatpur, Nepal.
dc.creator.affiliationCOMAT, Kathmandu, Nepal.
dc.creator.affiliationDepartment of Medicine, College of Medical Sciences, Bharatpur, Nepal.
dc.date.accessioned2026-10-29T05:56:35Z
dc.date.available2026-10-29T05:56:35Z
dc.date.issued2013
dc.description.abstractAbstract Introduction: Acute coronary syndrome is the major leading cause for coronary care unit admission. Its spectrum comprises a variety of disorders including unstable angina, non ST elevation and ST elevation myocardial infarction. Methods: An observational study was designed to study the spectrum of acute coronary syndrome and associated coronary heart disease risk factors in subjects admitted in intensive care unit from August 2009 to September 2010. Details including coronary risk factors and the categories and outcomes of acute coronary syndrome were analyzed. Results: A total of 57 subjects were included in the study. The majority (63.1%) were males. The mean age was 64.54±13.8 years.  Five (8.8%) patients were ≤45 years and 29 (50.88%) patients were ≥65 years. Majority of the patients were smokers (50.87%). The other major coronary heart disease risk factors were diabetes (43.85%), hypertension (36.87%), dyslipidemia (26.32%) and previous history of coronary heart disease (31.58%). Coronary heart disease figured prominently in the family history as well (26.32%). ST elevation myocardial infarction was the major category (42.11%) followed by non-ST elevation myocardial infarction and unstable angina (31.58% and 26.32% respectively). Myocardial infarction complicated with cardiogenic shock had very high mortality (83.33%).  Conclusions: The ST elevation myocardial infarction was the major clinical form of acute coronary syndrome admitted in intensive care unit. Prevention should be targeted on modifiable risk factors such as the management of risk factors. In addition, the improvement in cardiology service with the establishment of CCU and cathlab might alter the mortality and morbidity in ACS management. Keywords: Acute coronary syndrome; Coronary risk factors; Intensive care unit.
dc.identifier.doihttps://doi.org/10.31729/jnma.1897
dc.identifier.urihttps://hdl.handle.net/20.500.14572/8207
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectAcute coronary syndrome
dc.subjectCoronary risk factors
dc.subjectIntensive care unit
dc.titleAcute coronary syndrome in an intensive care unit of a tertiary care centre: the spectrum and coronary risk factors
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage321
oaire.citation.startPage316
relation.isJournalIssueOfPublication22c338ba-3239-42cd-b94b-32397e5e8b5a
relation.isJournalIssueOfPublication.latestForDiscovery22c338ba-3239-42cd-b94b-32397e5e8b5a
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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