Article:
Heart failure with preserved EF: a bird eye view

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorFahad Aziz
dc.contributor.authorLuqman-Arfath Thazhatauveetil-Kunhahamed
dc.contributor.authorChijioke Enweluzo
dc.contributor.authorMisbah Zaeem
dc.creator.affiliationWake Forest School of Medicine, 295 Chelsea Village Cir, Winston Salem, NC 27103, USA.
dc.creator.affiliationWake Forest School of Medicine, 295 Chelsea Village Cir, Winston Salem, NC 27103, USA.
dc.creator.affiliationWake Forest School of Medicine, 295 Chelsea Village Cir, Winston Salem, NC 27103, USA.
dc.creator.affiliationWake Forest School of Medicine, 295 Chelsea Village Cir, Winston Salem, NC 27103, USA.
dc.date.accessioned2026-10-29T07:42:40Z
dc.date.available2026-10-29T07:42:40Z
dc.date.issued2013
dc.description.abstractAbstract The concept of ‘‘diastolic’’ heart failure grew out of the observation that many patients who have the symptoms and signs of heart failure had an apparently normal left ventricular (LV) ejection fraction. Thus it was assumed that since systolic function was ‘‘pre- served’’ the problem must lie in diastole, although it is not clear by whom or when this assumption was made. Diastolic heart failure is associated with a lower annual mortality rate of approximately 8% as compared to annual mortality of 19% in heart failure with systolic dysfunction, however, morbidity rate can be substantial. Thus, diastolic heart failure is an important clinical disorder mainly seen in the elderly patients with hypertensive heart disease. Early recognition and appropriate therapy of diastolic dysfunction is advisable to prevent further progression to diastolic heart failure and death. There is no specific therapy to improve LV diastolic function directly. Medical therapy of diastolic dysfunction is often empirical and lacks clear-cut pathophysiologic concepts. Nevertheless, there is growing evidence that calcium channel blockers, beta-blockers, ACE-inhibitors and ARB as well as nitric oxide donors can be beneficial. Treatment of the underlying disease is currently the most important therapeutic approach. Keywords: Diastolic heart failure; Doppler echocardiography; Treatment.
dc.identifier.doihttps://doi.org/10.31729/jnma.1628
dc.identifier.urihttps://hdl.handle.net/20.500.14572/8225
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectDiastolic heart failure
dc.subjectDoppler echocardiography
dc.subjectTreatment
dc.titleHeart failure with preserved EF: a bird eye view
dc.typeArticle
dspace.entity.typePublication
local.article.typeReview Article
oaire.citation.endPage412
oaire.citation.startPage405
relation.isJournalIssueOfPublication22c338ba-3239-42cd-b94b-32397e5e8b5a
relation.isJournalIssueOfPublication.latestForDiscovery22c338ba-3239-42cd-b94b-32397e5e8b5a
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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