Publication:
Associated Factors and Outcome of Babies Born Through Meconium Stained Amniotic Fluid

creativeworkseries.issn1812-2027
dc.contributor.authorShrestha, A
dc.contributor.authorSingh, SD
dc.contributor.authorTamrakar, D
dc.date.accessioned2025-11-20T07:14:10Z
dc.date.available2025-11-20T07:14:10Z
dc.date.issued2018
dc.descriptionShrestha A,1 Singh SD,1 Tamrakar D2 1Department of Pediatrics 2Department of Community Medicine Kathmandu University School of Medical Sciences Dhulikhel, Kavre, Nepal
dc.description.abstractABSTRACT Background Neonates born through meconium stained amniotic fluid (MSAF) are associated with significant morbidity and mortality. Objective To study the incidence, associated factors and outcome of meconium stained amniotic fluid babies born in Dhulikhel hospital. Method Prospective, cross-sectional study conducted in Obstetric ward and Neonatal Intensive Care Unit (NICU) from 15 December 2015 to 15 December 2016. All the babies born through meconium stained amniotic fluid during the period were included. Result Incidence of meconium stained amniotic fluid was 6.5%(167/2581). Meconium aspiration syndrome (MAS) developed in 9(5.4%) among all meconium stained amniotic fluid cases. Primigravidity and postdatism were observed more in Meconium aspiration syndrome group than meconium stained amniotic fluid group (77.8% VS 73.4%; 33.3% VS 26.3%). Babies delivered by caesarian section were more in meconium stained amniotic fluid group than Meconium aspiration syndrome group (47.5% VS 33.3%). All the babies with meconium stained amniotic fluid improved except one baby with Meconium aspiration syndrome who expired. Neonatal sepsis was a significant co-morbidity in Meconium aspiration syndrome group (P value= 0.008). There was increased incidence of operative delivery in thick meconium stained amniotic fluid than thin meconium stained amniotic fluid (52.6% VS 38.9%). Similarly, Neonatal Intensive Care Unit admission and neonatal complications like Meconium aspiration syndrome, perinatal asphyxia and sepsis were more commonly observed in thick meconium stained amniotic fluid group than thin meconium stained amniotic fluid group. Conclusion The progression to meconium aspiration syndrome in babies with meconium stained amniotic fluid is not associated with any maternal and neonatal factors studied. MAS babies are 10 times more likely to require NICU admission and sepsis is a significant co-morbidity. Thick meconium stained amniotic fluid is worrisome. There is increased chance of operative delivery and neonatal complications if associated with thick meconium stained amniotic fluid. KEY WORDS Meconium, Meconium aspiration syndrome, Meconium stained amniotic fluid
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3186
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectMeconium
dc.subjectMeconium aspiration syndrome
dc.subjectMeconium stained amniotic fluid
dc.titleAssociated Factors and Outcome of Babies Born Through Meconium Stained Amniotic Fluid
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage68
oaire.citation.startPage65
relation.isJournalIssueOfPublication356e7b89-3807-46a2-8df1-6e598f0a76a5
relation.isJournalIssueOfPublication.latestForDiscovery356e7b89-3807-46a2-8df1-6e598f0a76a5
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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