Publication: Minimal Change Disease in an Adult: A Case Report
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Minimal change disease is an important cause of nephrotic syndrome in children, however, few cases are seen among adults. There is very little literature regarding the occurrence of minimal change disease in adults. We reported a case of a 63-year-old male who presented with the complaint of swelling around the eyes mostly during the morning for 18 days and frothing of urine for 7 days. On examination, the patient was ill-looking and had edema around the eyes and over the ankles. After preliminary investigations, renal biopsy was performed and electron microscopy revealed diffuse effacement of foot processes of visceral epithelial cells suggesting minimal change disease (podocytopathy). The patient has been treated with tablet prednisolone 60 mg per oral once daily, tablet ramipril 2.5 mg per oral once daily, and tablet torsemide 20 mg per oral twice daily. Hence, minimal change disease should also be considered as a differential diagnosis in adults presenting with the features of nephrotic syndrome.
Description
Shashank Neupane
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
https://orcid.org/0000-0001-5339-8962
Prasamsa Pudasaini
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Anupam Sharma
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Shriya Sharma
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Aakriti Adhikari
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Kumar Roka
Department of Internal Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal
Keywords
Electron microscopy, Minimal change disease, Nephrotic syndrome, Prednisolone