Article:

Acid-neutralizing capacity and acid-neutralizing profile of various antacid formulations available in Nepal

Abstract The relative effectiveness of treatment, acid-neutralizing capacity and acid-neutralizing profiles are inter-related. Their inter-relation is evaluated in-vitro by USP/BP method and encouraging results are found. Hydroxide forms of aluminium and magnesium combination are found to be more effective than the combination of aluminium hydroxide and magnesium trisilicate. Rationality of choosing solid or liquid form of antacid formulations are also discussed. Keywords: Antacid, acid-neutralizing capacity