Publication:
Association of Androgenetic Alopecia with Benign Prostatic Hyperplasia: A Case Control Study

creativeworkseries.issnISSN 2091-0231 eISSN 2091-167X
dc.contributor.authorChaudhary, Manoj Kumar
dc.contributor.authorAgrawal, Sudha
dc.contributor.authorAgrawal, Chandra Shekhar
dc.date.accessioned2025-08-21T11:06:10Z
dc.date.available2025-08-21T11:06:10Z
dc.date.issued2018
dc.descriptionManoj Kumar Chaudhary BP Koirala Institute of Health Sciences Sudha Agrawal BP Koirala Institute of Health Sciences, Dharan Chandra Shekhar Agrawal BP Koirala Institute of Health Sciences, Dharan
dc.description.abstractAbstract Introduction: Androgenetic alopecia (AGA) is associated with increased risk of several systemic diseases and some environmental factors, however, controversies exist. Since AGA and Benign Prostatic Hyperplasia (BPH) share common pathogenesis and AGA manifests some decades before BPH onset, it may serve as an early marker of BPH. Objective: This study was conducted to know AGA and its association with BPH in men ≥20 years of age. Materials and Methods: Clinically diagnosed cases of AGA (n=176) and 117 age matched healthy controls were enrolled. All cases and controls were subjected for abdomino-pelvic ultrasonography, urinary flowmetry, fasting lipid profiles, glycemic index and body mass index. International Prostate Symptom Score (IPSS) was also assessed. Results: Among 176 patients, 120 (68.18%) had Hamilton-Norwood grade III AGA and 56 (31.82%) had grade IV-VII AGA. In both groups, 140 (79.55%) cases and 93 (79.49%) controls were aged <35 years respectively. Family history of AGA was present in 108 (61.36%) cases and 2 (1.71%) controls. This observation was statistically significant with OR= 89.61 (95%CI 23.67-339.29). Three (1.7%) cases and none of the controls had prostate volume >30ml. Seventeen (9.66%) cases and 4 (3.42%) controls were graded as moderately/severely symptomatic IPSS. Statistically significant association was seen between family history and early onset of hair loss (<35 years) in a male sibling or parent. Conclusion: Although positive family history was associated with early onset of AGA, no association between AGA and BPH could be elicited in our study. Keywords: Alopecia, body mass index, glycemic index, lipids, prostatic hyperplasia
dc.identifierhttps://doi.org/10.3126/njdvl.v16i1.19399
dc.identifier.urihttps://hdl.handle.net/20.500.14572/1909
dc.language.isoen_US
dc.publisherSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
dc.titleAssociation of Androgenetic Alopecia with Benign Prostatic Hyperplasia: A Case Control Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage23
oaire.citation.startPage17
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relation.isJournalIssueOfPublication.latestForDiscoveryb96994f1-d831-480e-a217-e24faace1d83
relation.isJournalOfPublicationb2ab7aab-75b0-4bd1-9ed0-b8a91c68201a

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