Publication:
Ventilator Associated Pneumonia in Tertiary Care Hospital, Maharajgunj, Kathmandu, Nepal

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creativeworkseries.issnISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987
dc.contributor.authorShrestha, RK
dc.contributor.authorDahal, RK
dc.contributor.authorMishra, SK
dc.contributor.authorParajuli, K
dc.contributor.authorRijal, BP
dc.contributor.authorSherchand, JB
dc.contributor.authorKirikae, T
dc.contributor.authorOhara, H
dc.contributor.authorPokhrel, BM
dc.date.accessioned2026-05-15T05:08:31Z
dc.date.available2026-05-15T05:08:31Z
dc.date.issued2013
dc.descriptionRK Shrestha Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal RK Dahal Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal SK Mishra Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal K Parajuli Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal BP Rijal Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal JB Sherchand Department of Microbiology, National Medical College and Teaching Hospital, Birganj, Parsa, Nepal. T Kirikae Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal H Ohara National Centre for Global Health and Medicine (NCGM) Tokyo,Japan BM Pokhrel Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
dc.description.abstractAbstract Introduction: Ventilator Associated Pneumonia (VAP) is the most common nosocomial infection among intensive care unit (ICU) patients and lack of much information in Nepal. So, the aim of this study was to determine prevalence and bacteriological profile of VAP with special reference to multi-drug resistant (MDR), Methicillin-resistant Staphylococcus aureus(MRSA), Metallo-β-Lactamase(MBL), Extended-Spectrum β-Lactamase(ESBL)-producing bacterial strains. Methods: A total 150 tracheal specimens were studied during June 2011 to May 2012 at Department of Microbiology, TUTH as described by American Society for Microbiology (ASM). Combination disk method was done for the detection of ESBL and MBL producing isolates. Results: Prevalence of VAP was found to be 34%. Acinetobactereal coaccticusbaumannii complex (44%) was the commonest isolate, followed by Klebsiellapneumoniae (22%), Pseudomonas aeruginosa (16%) and Staphylococcus aureus (12%). Among MDR Gram negative bacteria (GNB), 39% were MBL and 33% were ESBL-producers. All GNB (61) were sensitive to Polymyxin B and Colistinsulphate, whereas, 48% were found resistant to Carbapenems. Prevalence of MRSA was 75%, which were all sensitive to Vancomycin. Conclusion: High prevalence of VAP, MDR along with MRSA or ESBL or MBL producing strains was found in the study. Thus, suitable control measures must be adopted to cope up this alarming situation with genetic characterization. Keywords: VAP, ICU, MDR, MRSA, ESBL, MBL
dc.identifierhttps://doi.org/10.59779/jiomnepal.626
dc.identifier.urihttps://hdl.handle.net/20.500.14572/6090
dc.language.isoen_US
dc.publisherInstitute of Medicine
dc.subjectVAP
dc.subjectICU
dc.subjectMDR
dc.subjectMRSA
dc.subjectESBL
dc.subjectMBL
dc.titleVentilator Associated Pneumonia in Tertiary Care Hospital, Maharajgunj, Kathmandu, Nepal
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage28
oaire.citation.startPage21
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relation.isJournalIssueOfPublication.latestForDiscoverye6f96d43-7cad-4fa0-b6ab-c8622f4864eb
relation.isJournalOfPublicationa9ba45d9-ee33-4a6b-b1fc-6626b87eec6c

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