Publication: Metronidazole Induced Cerebellar Toxicity: A Case Report
Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Metronidazole is a widely used antibiotic against bacterial and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We present a case of a 55-years male presented with dysarthria, who had positive cerebellar sign and magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for two months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole.
Description
Shova Sapkota
Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0003-4463-055X
Aliska Niroula
Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
Rina Prajapati
Department of Neurology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0002-0876-6268
Subhani Sharma
Department of Neurology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
Krishna Dhungana
Department of Neurology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0002-2693-5926
Keywords
case report, cerebellar toxicity, metronidazole, side effect