Publication: Clinico-etiological Profile of Seizure Disorder among Adults Admitted to Tertiary Care Hospital of Nepal
Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Medicine
Abstract
ABSTRACT
Introduction
Seizures beginning in the adult life require special attention as regards to their etiology because these are likely to be due to an identifiable cause. Understanding the trend in prevalence of various etiology of seizure will help in formulation of diagnostic protocol and might help to reduce the cost of investigations. In this retrospective study, we, therefore, aimed to assess etiology and clinical profile of adult onset seizures.
Methods
This was a retrospective study done at Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal. We included patients of both sexes and age > 18 years old admitted to neurology ward with seizure disorder and excluded the patients who suffered from unprovoked seizure and epilepsy. Our study variables included demographic profile of patients, co-morbidities, clinical features, laboratory investigation, neuro-imaging, EEG and drugs.
Results
Among 26 patients, 3 (11.5%) had hyponatremia, 2(7.7%) had intra-cranial space occupying lesion, 12(46.2%) had neurocysticercosis (NCC), 1 (3.8%) had opioid withdrawal, 1 (3.8%) had alcohol withdrawal, 1 (3.8%) had stroke, 1 (3.8%) tuberculoma and in 5 (19.2%) patients no underlying cause was found.
Conclusion
NCC was the most common cause of seizure disorders among adults. Even after huge development in laboratory, neuroimaging and neurophysiology testing, in as much as 19.2% patients, no etiology could be found.
Keywords: Adults, outcome, seizure, tertiary care hospital
Description
Parash Rayamahji, Ragesh Karn, Bikram P Gajurel, Reema Rajbhandari, Rajeev Ojha, Jagadish P Agrawal
Department of Neurology, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu
Keywords
Adults, outcome, seizure, tertiary care hospital