Publication: Pathologies En-Route of Oral Basaloid Malignancies to Basaloid Squamous Cell Carcinoma
Date
2014
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Accurate histopathological diagnosis of any tumour is imperative because of
variable prognostic and clinical implications. Basaloid squamous cell carcinoma
(BSCC) is a rare distinctive histological variant of oral squamous cell carcinoma
(OSCC) exhibiting an aggressive clinical course and poor prognosis. The advanced
stage of presentation is speculatively responsible for this biological behaviour
which is manifested by development of metastasis and subsequently poor survival.
However, the non-specific clinical appearance and histopathological resemblance
of BSCC with OSCC and other oral basaloid malignancies (OBM) especially in limited
sample size poses diagnostic difficulties. The article emphasizes on the diagnostic
criteria and pitfalls encountered in making the differential diagnosis of BSCC from
OBMs along with report of a case presented at a dental college in January 2012.
KEY WORDS
Basaloid squamous cell carcinoma, differential diagnosis, oral basaloid malignancy,
oral squamous cell carcinoma
Description
Mehendiratta M,1 Rehani S,1 Kumra M,1 Shah MK2
1Department of Oral and Maxillofacial Pathology
Sudha Rustagi Dental College and Research Institute Haryana
2Department of Hematology, St. Stephen’s Hospital Delhi, India