Publication: Zoledronic Acid in Treatment of Calcinosis in a boy with Juvenile Dermatomyositis – A Case Report
Date
2024
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Perinatal Society of Nepal (PESON)
Abstract
Abstract:
Calcinosis cutis is one of the dermatological manifestations of juvenile dermatomyositis. We present a case of an eight year old boy who presented with proximal myopathy, Gottron papules and heliotrope rash. Raised muscle enzymes and electromyography confirmed the diagnosis of juvenile dermatomyositis; and treatment started with steroids and methotrexate. Patient had poor compliance and three years later, presented with multiple calcinotic lesions over lower abdomen, buttocks and thighs. Due to lack of improvement in calcinosis after six months of treatment with steroids and methotrexate; 3-monthly zoledronic acid and fortnightly etanercept were started. After one year, patient is in remission with improved calcinosis.
Description
Fazaila Jabeen
Department of Paediatric Medicine, University of Child Health Sciences, The Children’s Hospital, Ferozepur Rd, Nishtar Town, Lahore, Punjab 54000, Pakistan.
Shadab Masood
Department of Paediatric Medicine, University of Child Health Sciences, The Children’s Hospital, Ferozepur Rd, Nishtar Town, Lahore, Punjab 54000, Pakistan.
Samia Naz
Department of Paediatric Medicine, University of Child Health Sciences, The Children’s Hospital, Ferozepur Rd, Nishtar Town, Lahore, Punjab 54000, Pakistan.
Keywords
Calcinosis, etanercept, Juvenile dermatomyositis, zoledronic Acid