Publication: Perioperative Outcomes following Surgery of Brain Tumors: Assessment and Analysis of Risk Factors
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Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Medicine
Abstract
ABSTRACT
Introduction: Cranial neurosurgery carries significant morbidity and mortality. Hence it is imperative to combine the latest available technological equipment with surgeon’s experience to prevent or reduce perioperative complications. It is also equally important to have a preoperative general assessment of the patient with functional status in particular to predict postoperative outcomes.
Methods: This is a prospective study consisting of 122 patients selected over a period of 5 years (March 2017-March 2022). The patient database was retrieved from the medical record department, Nobel Institute of Neurosciences, Nobel Medical College Teaching Hospital, Biratnagar, Nepal and the approval of Institutional review committee was obtained. Age, gender, tumor related factors (site, extent and size), preoperative Glasgow Coma Scale (GCS) score, Karnofsky Performance Status (KPS) score and Modified Rankin scale (mRS) grade and their correlation with patient’s perioperative outcome were assessed.
Results: Significant correlation was found between preoperative KPS score, mRS grade and patient’s perioperative outcome (low KPS score <70 and high mRS grade was associated with adverse outcomes). There was no positive correlation between age, gender and tumor related factors with outcomes.
Conclusion: Low KPS score <70 and a high Modified Rankin scale score were associated with adverse perioperative outcomes in patient’s undergoing elective craniotomy for brain tumor surgery.
Keywords: Brain tumor; preoperative KPS (Karnofsky performance status score); preoperative mRS (Modified Rankin scale score)
Description
Prakash Kafle1, Phelix Rufus2, Nabin Paudyal1, Narendra P Joshi1, Babita Khanal3, Edmond Jonathan4, Binod R Bhandari5, Mohan R Sharma6
1Nobel Institute of Neurosciences, Department of Neurosurgery, Nobel Medical College Teaching Hospital, Biratnagar, Nepal
2Bangalore Baptist Hospital, Hebbal, Bangalore, Karnataka, India
3Department of Pediatric Medicine, Nobel Medical College Teaching Hospital, Biratnagar, Nepal
4Christian Medical College and Hospital, Vellore, Tamil Nadu, India
5Bir Hospital, Kathmandu, Nepal
6Department of Neurosurgery, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal
Keywords
Brain tumor, preoperative KPS (Karnofsky performance status score), preoperative mRS (Modified Rankin scale score)