Article:
Post COVID-19 infection in subclinical hyperthyroidism among patients attending a Tertiary Hospital in Kathmandu

creativeworkseries.issnOnline ISSN: 2676-1424; Print ISSN: 2676-1319
dc.contributor.authorAdhikari, Prabin
dc.contributor.authorSingh, Rasu
dc.creator.affiliationDepartment of Internal Medicine, Nepal Medical College Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Internal Medicine, Nepal Medical College Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.date.accessioned2026-10-29T03:55:38Z
dc.date.available2026-10-29T03:55:38Z
dc.date.issued2024
dc.description.abstractAbstract: Coronavirus disease 2019 (COVID-19) infection may induce thyroid dysfunction as Coronavirus 2 (SARS-CoV-2) can invade the human tissue cells through the cell receptor of angiotensin-converting enzyme 2 (ACE2), expression of which is high in thyroid tissue. The aim of the present study was to assess the subclinical hyperthyroidism post-COVID-19 effects on thyroid function in patients without history of thyroid disease after complete recovery from mild-to-severe COVID19 and find the prevalence of subclinical hyperthyroidism. A descriptive cross-sectional study was conducted in the Department of Internal Medicine, of tertiary care center from September 2022 to February 2023 after obtaining ethical approval from the Institutional Review Committee of Nepal Medical College (Ref. No.: 15-079/080). Convenience sampling method was used among patients who met the eligibility criteria. Point estimate at 95.0% confidence interval were calculated along with frequency and proportion for binary data. Out of 38 patients, 34 (89.5%) had thyroid dysfunction. Among them, 7 (20.6%) had subclinical hyperthyroidism, 2 (5.9%) had thyroiditis and 1 (2.9%) had Graves’ disease. Those who had thyroid dysfunction, 10 (29.4%) people were diagnosed with hyperthyroidism. The hyperthyroidism among COVID-19 patients is a common finding and subclinical hyperthyroidism was seen in 20.6% of patients post COVID-19. Therefore, while managing COVID-19, patients’ thyroid profile should be considered.
dc.identifier.doihttps://doi.org/10.3126/nmcj.v26i1.63871
dc.identifier.urihttps://hdl.handle.net/20.500.14572/8189
dc.language.isoen_US
dc.publisherNepal Medical College Pvt. Ltd.
dc.subjectCOVID-19
dc.subjectthyroid dysfunction
dc.subjectHyperthyroidism
dc.titlePost COVID-19 infection in subclinical hyperthyroidism among patients attending a Tertiary Hospital in Kathmandu
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage4
oaire.citation.startPage1
relation.isJournalIssueOfPublicationad330a3e-75f1-4484-8269-5d082cde50f7
relation.isJournalIssueOfPublication.latestForDiscoveryad330a3e-75f1-4484-8269-5d082cde50f7
relation.isJournalOfPublication865934c8-5e95-468c-8ca6-7bb2529e4064

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