Publication: Autoimmune Thyroid Disease in Patients with Hypovitaminosis D in Department of Biochemistry of a Tertiary Care Centre: A Descriptive Cross-sectional Study
| creativeworkseries.issn | JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X | |
| dc.contributor.author | Sherchand, Ojaswee | |
| dc.contributor.author | Niraula, Apeksha | |
| dc.contributor.author | Mishra, Bijaya | |
| dc.contributor.author | Subedi, Manish | |
| dc.contributor.author | Maskey, Robin | |
| dc.date.accessioned | 2025-12-10T09:44:00Z | |
| dc.date.available | 2025-12-10T09:44:00Z | |
| dc.date.issued | 2022 | |
| dc.description | Ojaswee Sherchand Department of Biochemistry, Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal Apeksha Niraula Department of Biochemistry, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Bijaya Mishra Department of Biochemistry, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal Manish Subedi Department of Internal Medicine, Mechi Zonal Hospital, Bhadrapur, Jhapa, Nepal Robin Maskey B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal | |
| dc.description.abstract | Abstract Introduction: Autoimmune thyroid disease is characterised by the generation of autoantibodies against self-antigens such as thyroid peroxidase, thyroglobulin, and thyroid-stimulating hormone receptor. Recent studies have implicated the role of hypovitaminosis D to immune dysfunction, failure of self-tolerance and generation of autoantibodies. This study aimed to find out the prevalence of autoimmune thyroid disease among hypovitaminosis D patients in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among participants between the ages of 18 years to 65 years who visited the Department of Biochemistry of a tertiary care centre between the periods of July 2018 to December 2019. The study was initiated after receiving ethical approval from the Institutional Review Committee (Reference number: 42,8/074/075-IRC). Data was collected using a self-administered questionnaire followed by anthropometric measurement and blood collection. Thyroid hormone, thyroid peroxidase antibody and 25-hydroxy vitamin D were measured by chemiluminescence technique. Convenience sampling was used. Point estimate and 95% Confidence Interval were calculated. Results: Among 83 patients, 39 (46.98%) (42.32–51.63, 95% Confidence Interval) had autoimmune thyroid disease. Conclusions: The prevalence of autoimmune thyroid disease among patients with hypovitaminosis D was similar to studies conducted in comparable settings. | |
| dc.identifier | https://doi.org/10.31729/jnma.7493 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/3515 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Medical Association | |
| dc.subject | Autoimmune diseases | |
| dc.subject | Prevalence | |
| dc.subject | Thyroid | |
| dc.subject | Vitamin D | |
| dc.title | Autoimmune Thyroid Disease in Patients with Hypovitaminosis D in Department of Biochemistry of a Tertiary Care Centre: A Descriptive Cross-sectional Study | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 603 | |
| oaire.citation.startPage | 600 | |
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