Publication:
Prevalence of Pulmonary Tuberculosis in HIV-Infected Individuals

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creativeworkseries.issn1999-6217
dc.contributor.authorPokhrel, Shisir
dc.contributor.authorRegmi, Sanjib Mani
dc.contributor.authorGhimire, Kripa
dc.contributor.authorPaudel, Samjhana
dc.contributor.authorPaudel, Aarjawee
dc.contributor.authorTimilsina, Sanjog
dc.contributor.authorShrestha, Nirmala
dc.contributor.authorPaudel, Amrita
dc.contributor.authorPokhrel, Bedana
dc.contributor.authorSharma, Damodar
dc.contributor.authorKoirala, Bidhya
dc.contributor.authorBhattarai, Sudip
dc.contributor.authorJoshi, Pratikshya
dc.contributor.authorBhatta, Roshan
dc.date.accessioned2026-08-20T03:50:06Z
dc.date.available2026-08-20T03:50:06Z
dc.date.issued2026
dc.descriptionShisir Pokhrel Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal https://orcid.org/0009-0009-8963-909X Sanjib Mani Regmi Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Kripa Ghimire Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Samjhana Paudel Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Aarjawee Paudel Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Sanjog Timilsina Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Nirmala Shrestha Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Amrita Paudel Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Bedana Pokhrel Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Damodar Sharma Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Bidhya Koirala Pokhara Academy of Health Sciences, Kaski, Pokhara, Nepal Sudip Bhattarai Pokhara University, Kaski, Pokhara Pratikshya Joshi Manmohan Memorial Institute of Medical Sciences, Kathmandu, Nepa Roshan Bhatta Nepal Health and Research Council, Kathmandu
dc.description.abstractAbstract: Background: Tuberculosis (TB) is a significant cause of mortality among people living with HIV (PLWH), in Nepal. HIV increases the risk of progression from latent to active TB, increasing mortality. Despite established TB control programs, there is a significant lack of recent data measuring the tuberculosis burden among PLWH specially within the Western region of Nepal. This study was conducted to assess the prevalence of pulmonary tuberculosis among HIV-positive patients attending a tertiary care centre in Gandaki Province, Nepal. Methods: A hospital-based cross-sectional study was conducted at Western Regional Hospital, Pokhara Academy of Health Sciences, from August 2025 to January 2026. First, HIV-positive patients attending the ART clinic were screened, and those aged ?18 years without prior tuberculosis were included. Next, participants were recruited using convenience sampling. After obtaining informed consent, sociodemographic and clinical data were collected through a structured questionnaire and medical record review. Subsequently, CD4 counts were measured using the PIMA CD4 analyser, and sputum samples were examined using Ziehl–Neelsen staining for acid-fast bacilli. Finally, data were analysed using SPSS version 22, with p < 0.05 considered statistically significant. Results: Prevalence of pulmonary TB was found to be 5.1% among 137 participants. TB co-infection was found to be higher among males and in the 20-29 years and >70 years age groups. TB was more common among those with CD4 counts <200 cells/µL, but was not statistically significant. Conclusions: The study found a 5.1% prevalence of pulmonary TB among PLWH in western Nepal and highlights the need for regular TB screening. Keywords: CD4 count; pulmonary tuberculosis Nepal; TB–HIV co-infection.
dc.identifierhttps://doi.org/10.33314/jnhrc.v24i01.5271
dc.identifier.urihttps://hdl.handle.net/20.500.14572/7365
dc.language.isoen_US
dc.publisherNepal Health Research Council
dc.subjectTuberculosis
dc.subjectHIV
dc.subjectTB–HIV co-infection
dc.subjectPulmonary tuberculosis
dc.subjectCD4 count
dc.subjectNepal
dc.subjectPLWH
dc.titlePrevalence of Pulmonary Tuberculosis in HIV-Infected Individuals
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage132
oaire.citation.startPage126
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relation.isJournalIssueOfPublication.latestForDiscoverya1c63b20-6d6e-4473-9408-632d1b427f81
relation.isJournalOfPublication40bd2739-8b19-447c-be60-723a1bdd1dcd

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