Publication: Progressive Pulmonary Disease in X-Linked Agammaglobulinemia despite Regular Immunoglobulin Replacement: A Case Report
| creativeworkseries.issn | ISSN 1990-7974 eISSN 1990-7982 | |
| dc.contributor.author | Laaraje, Azzeddine | |
| dc.contributor.author | Boucaid, Abdelhalim | |
| dc.contributor.author | RadiI, Abdelilah | |
| dc.contributor.author | Abilkassem, Rachid | |
| dc.date.accessioned | 2025-10-13T10:43:50Z | |
| dc.date.available | 2025-10-13T10:43:50Z | |
| dc.date.issued | 2024 | |
| dc.description | Azzeddine Laaraje Department of Paediatrics, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco Abdelhalim Boucaid Department of Pulmonology and Allergology, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco Abdelilah RadiI Department of Paediatrics, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco Rachid Abilkassem Department of Paediatrics, Mohammed V Military Training Hospital, Mohammed V University, Rabat, Morocco | |
| dc.description.abstract | Abstract: X-linked agammaglobulinemia (XLA) is characterized by early-onset recurrent bacterial infections, particularly affecting the respiratory tract. We report a 12-year-old male with XLA who presented with chronic cough and recurrent respiratory infections. Genetic testing confirmed a BTK gene mutation. Radiological findings revealed diffuse cylindrical bronchiectasis with bilateral bronchial wall thickening, and pulmonary function tests showed a mixed severe ventilatory pattern. Despite regular immunoglobulin replacement therapy, the patient developed chronic lung disease, highlighting the need for early diagnosis and aggressive management of respiratory manifestations. | |
| dc.identifier | https://doi.org/10.60086/jnps1266 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/2644 | |
| dc.language.iso | en_US | |
| dc.publisher | Perinatal Society of Nepal (PESON) | |
| dc.subject | X-Linked Agammaglobulinemia | |
| dc.subject | Progressive Pulmonary Disease | |
| dc.subject | Immunoglobulin Replacement | |
| dc.title | Progressive Pulmonary Disease in X-Linked Agammaglobulinemia despite Regular Immunoglobulin Replacement: A Case Report | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Case Report | |
| oaire.citation.endPage | 47 | |
| oaire.citation.startPage | 44 | |
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