Publication: Serum Vitamin B12 Level in Children with Type 1 Diabetes
| creativeworkseries.issn | 1999-6217 | |
| dc.contributor.author | Pradhan, Santosh | |
| dc.contributor.author | Thapa, Subhana | |
| dc.contributor.author | Shrestha, Pradeep Krishna | |
| dc.contributor.author | Jha, Bharat | |
| dc.date.accessioned | 2025-07-10T10:45:57Z | |
| dc.date.available | 2025-07-10T10:45:57Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Abstract Background: Type 1 Diabetes Mellitus is known to be associated with multiple co-morbidities. Vitamin B12 deficiency is a potential co- morbidity that might have been overlooked in these patients. The aim of this study is to evaluate the serum level of vitamin B 12 in a well-defined population of Type 1 diabetes. Methods: The cross sectional study carried out on 40 patients with Type 1 Diabetes Mellitus visiting endocrinology unit in Kanti children’s Hospital, Kathmandu, Nepal. Thirty healthy non diabetics were also selected. Serum C-peptide, vitamin B12, creatinine, blood glucose level and glycosylated hemoglobin were assessed in both groups. SPSS ver. 22 was used to analyze the data. Results:The mean serum vitamin B12 level of the diabetic group was 206.92±82.18 pmol/L. Among the population 40.0% i.e. 16 out of 40 were found to be deficient and 37.5 % i.e. 15 out of 40 were subclinically deficient. Whereas the mean serum vitamin B12 level of the non diabetic group was 340.71±136.02pmol/L. Out of 30 only 2(6.7%) were deficient, 8 (26.75%) were found to be subclinically deficient. Significant difference was noticed in the mean serum level of vitaminB12 between these two groups. Conclusions: This study shows the presence of low serum vitamin B12 levels in Type 1 Diabetics. The routine screening for this condition along with confirmatory test and detail clinical examination could benefit the patients with Type 1 diabetes. Keywords: Autoimmune disease; Type 1 Diabetes mellitus; Vitamin B12. | |
| dc.identifier | https://doi.org/10.33314/jnhrc.v23i01.4726 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/81 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Health Research Council | |
| dc.title | Serum Vitamin B12 Level in Children with Type 1 Diabetes | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 20 | |
| oaire.citation.startPage | 14 | |
| relation.isJournalIssueOfPublication | 710a5a58-3a9b-4cdc-9898-5e7769f7ec25 | |
| relation.isJournalIssueOfPublication.latestForDiscovery | 710a5a58-3a9b-4cdc-9898-5e7769f7ec25 | |
| relation.isJournalOfPublication | 40bd2739-8b19-447c-be60-723a1bdd1dcd |