Publication:
Histiocytosis Syndromes of Childhood: A report of four cases

creativeworkseries.issnISSN 1990-7974 eISSN 1990-7982
dc.contributor.authorRamesh, M
dc.contributor.authorSingh, V
dc.contributor.authorGhuliani, R
dc.contributor.authorKapur, BN
dc.contributor.authorSingh, J
dc.contributor.authorShankar, S
dc.date.accessioned2026-06-04T10:40:55Z
dc.date.available2026-06-04T10:40:55Z
dc.date.issued2010
dc.descriptionM Ramesh Resident, Dept of Paediatrics, Armed Forces Medical College, Pune, Maharashtra V Singh Resident, Dept of Paediatrics, Armed Forces Medical College, Pune, Maharashtra R Ghuliani Sr.Advisor, Dept of Paediatrics, Command Hospital, Southern Command, Pune, Maharashtra, India BN Kapur Sr. Advisor, Dept of Medicine & Oncology, Command Hospital, Southern Command, Pune, Maharashtra, India J Singh Classified Specialist, Dept of Medicine, Clinical Hematology & Oncology, Command Hospital, Southern Command, Pune, Maharashtra, India S Shankar Immunology, Reader, Dept of Medicine, Armed Forces Medical College, Pune, Maharashtra, India.
dc.description.abstractAbstract: Histiocytosis Syndromes of Childhood (HSC) are a group of rare and diverse disorders characterized by aggressive proliferation or accumulation of cells of monocyte - macrophage system of bone marrow. The clinical spectrum of this syndrome is distinctly varied. The exact pathophysiology of HSC is yet to be determined; however, evidence suggests that one of the subtypes, Hemophagocytic Lymphohistiocytosis, is due to decreased Natural Killer cell activity, resulting in increased activation of other T cell subtypes and production of cytokines. We present four cases of HSC managed at our center between October 2008 & February 2010.
dc.identifierhttps://doi.org/10.3126/jnps.v30i3.3923
dc.identifier.urihttps://hdl.handle.net/20.500.14572/6371
dc.language.isoen_US
dc.publisherNepal Paediatric Society (JNPS)
dc.subjectHistiocytosis Syndromes of Childhood
dc.subjectLangerhan’s cell Histiocytosis (LCH)
dc.subjectHemophagocytic Lymphohistiocytosis (HLH)
dc.subjectMacrophage Activation Syndrome (MAS)
dc.titleHistiocytosis Syndromes of Childhood: A report of four cases
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage174
oaire.citation.startPage171
relation.isJournalIssueOfPublication606d4588-8be5-4d11-88f9-29697ba6b4e4
relation.isJournalIssueOfPublication.latestForDiscovery606d4588-8be5-4d11-88f9-29697ba6b4e4
relation.isJournalOfPublication6f9be05c-05a9-4a3e-a5b5-a19a15ab042c

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