Publication: Comparative study between bupivacaine heavy vs pethidine intrathecally to study early haemodynamic changes and postoperative analgesia in patients undergoing caesarean section
Date
2007
Authors
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Publisher
Kathmandu University
Abstract
Objective: To study early hemodynamic changes and duration of postoperative analgesia between two study groups
of intrathecal pethidine and bupivacaine heavy in patients undergoing caesarean section.
Methodology: Total number of 60 patients of ASA I and II, undergoing caesarean section were enrolled in the
study. All the patients were divided into two groups: Pethidine and Bupivacaine heavy. The dose of pethidine for
subarachnoid block was 1mg/kg and in Bupivacaine group 2.2ml of 0.5% bupivacaine heavy was given
intrathecally. Heart rate and blood pressure of all the patients were recorded before subarachnoid block. After giving
spinal anesthesia, the heart rate and blood pressure were monitored and recorded in different time intervals. The
duration of postoperative analgesia in all patients was recorded in postoperative ward. The APGAR Scores of the
babies were recorded in 1and 5 minutes after delivery. The data were statistically compared using independent
sample t-test.
Conclusion: The hemodynamic parameters (HR & BP) were compared in different time intervals. The difference in
heart rate and blood pressure at different time intervals in the two study groups were statistically insignificant as (p
> 0.05). The total duration of postoperative analgesia in patients receiving sole intrathecal pethidine was 8 hours and
30 minutes. Where as, in Bupivacaine group the duration was 2 hrs and 36 minutes. This has been found statistically
significant (p<0.05).
Description
Shrestha BR 1, Maharjan SK 2, Thapa C 3
1,2 Assistant Professor, 3 Medical Officer, Dept of Anesthesiology and ICU, Kathmandu Medical College,Sinamangal, Kathmandu, Nepal