Publication: Mean Urea Reduction Ratio among Patients Undergoing Hemodialysis at a Tertiary Care Centre: A Descriptive Cross-sectional Study
Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Introduction: Chronic kidney disease is a major cause of mortality with a prevalence of 6%. Over the past half-century, hemodialysis has been the most preferred modality of treatment for sustaining the life of patients with end-stage kidney disease. Despite hemodialysis being freely available, achieving adequacy in hemodialysis is a challenging task. Inadequate dialysis is responsible for the high mortality. This study aimed to find out the mean value of the urea reduction ratio among patients undergoing hemodialysis at a tertiary care centre.
Methods: This was a descriptive cross-sectional study conducted from 15 January 2023 to 15 April 2023. Ethical approval was taken from Institutional Review Committee (Reference number: UCMS/IRC/044/23). Patients aged >18 years, undergoing maintenance hemodialysis and giving informed and written consent were included in the study. Urea reduction rate and single-pool Kt/V were estimated. Convenience sampling method was used.
Results: Among 100 patients, the mean urea reduction ratio among the study population was 25.24±15.59%. Males represented 62 (62%) of the study population. The mean age was 47.9±14.74 years. Hypertension and Diabetes mellitus was found to be the leading cause of end-stage kidney disease with 61 (61%) and 27 (27%) respectively. The mean value of spKT/V was 0.73±0.162.
Conclusions: The mean urea reduction ratio was found to be lower than the other studies done in similar settings.
Description
Krishna Kumar Agrawaal
Nephrology Unit, Department of Internal Medicine, Universal College of Medical Sciences, Bhairahawa, Rupandehi, Nepal
Sanjog Kandel
Department of Internal Medicine, Universal College of Medical Sciences, Bhairahawa, Rupandehi, Nepal
Sudhan Devkota
Department of Internal Medicine, Universal College of Medical Sciences, Bhairahawa, Rupandehi, Nepal
Keywords
Chronic kidney disease, Dialysis, Hemodialysis