Article:
Prevalence of Hepatitis D among patients with Hepatitis B viral infection attending a tertiary care centre of Nepal

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorRegmi, Kiran
dc.contributor.authorShrestha, Jeetndra Kaji
dc.contributor.authorKC, Sudhamshu
dc.contributor.authorJaishi, Bikash
dc.contributor.authorKarki, Niyanta
dc.contributor.authorKhadka, Dipendra
dc.contributor.authorKhadka, Sandip
dc.creator.affiliationLiver Unit, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
dc.creator.affiliationLiver Unit, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
dc.creator.affiliationLiver Unit, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
dc.creator.affiliationLiver Unit, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
dc.creator.affiliationLiver Unit, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
dc.creator.affiliationLiver Unit, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
dc.creator.affiliationLiver Unit, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
dc.date.accessioned2026-09-17T09:19:02Z
dc.date.available2026-09-17T09:19:02Z
dc.date.issued2017
dc.description.abstractAbstract Introduction: Worldwide there is variation in prevalence of Hepatitis D viral infection. Superinfection and co infection with hepatitis B viral infection is known to occur in 15-20 million people. Methods: This was a descriptive cross-sectional hospital based study carried out in NAMS, Bir hospital, Kathmandu, Nepal from period of January 2017 to June 2017. Consecutive patients of chronic hepatitis B viral infection of HBsAg positive with more than two-time upper normal limit of ALT were enrolled and tested for HDV IgG. Results: Forty patients were enrolled during study period. Mean age was 30.9±12.2 years. Males were 28 (70%) and females 12 (30%). Most of the patients were asymptomatic for HBV infection 32 (80%). HBeAg negative chronic hepatitis was most commonly present in 31 (77.5%). Family history of Hepatitis B viral infection was seen in 7 (17.5%) and sexual promiscuity in 5 (12.5%) as the mode of acquisition of hepatitis B viral infection. HBcIgM was positive in three patients with mean HBV DNA of 4.97x105±4.5x105 IU/ml in HBeAg positive group. HDV IgG was negative in all patients. Conclusions: Coinfection and superinfection of hepatitis D virus were found to be uncommon at Bir hospital, Nepal. Keywords: HbsAg; HDV DNA; HDV IgG; Hepatitis B; Hepatitis D.
dc.identifier.doihttps://doi.org/10.31729/jnma.3378
dc.identifier.urihttps://hdl.handle.net/20.500.14572/7735
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectHbsAg
dc.subjectHDV DNA
dc.subjectHDV IgG
dc.subjectHepatitis B
dc.subjectHepatitis D
dc.titlePrevalence of Hepatitis D among patients with Hepatitis B viral infection attending a tertiary care centre of Nepal
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage420
oaire.citation.startPage417
relation.isJournalIssueOfPublication879289ff-bc63-435d-b0e3-5f2202d261ef
relation.isJournalIssueOfPublication.latestForDiscovery879289ff-bc63-435d-b0e3-5f2202d261ef
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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