Publication: Bruton’s X-Linked Agammaglobulinemia Presenting as Chronic Monoarticular Arthritis
Date
2012
Article Type
Case Report
Journal Title
Journal ISSN
ISSN 1990-7974 eISSN 1990-7982
Volume Title
Pages
Pages: 245 - 249
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Bruton’s X-Linked Agammaglobulinemia (XLA) is an X linked recessive primary immune deficiency disorder characterized by recurrent bacterial infections and failure to generate immunoglobulins of all isotypes due to the absence or profoundly decreased mature B cells and plasma cells, secondary to mutations in the Bruton’s tyrosine kinase (Btk) gene. The coexistence of chronic monoarticular arthritis in a patient with Bruton’s XLA has been described an uncommon presentation. We describe a 5 year-old boy with XLA and chronic monoarticular arthritis.
Description
Mani Kant Kumar
Assistant Professor, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar
Pankaj Kumar Patel
Assistant Professor, Department of Pathology, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar
Mohammad Mahtab Ali Tahir
Junior Resident, Department of Paediatrics, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar
Keywords
Bruton’s X-linked Agammaglobulinemia, Chronic monoarticular arthritis, Btk gene
Identifier
https://doi.org/10.3126/jnps.v32i3.6183