Publication: Clinical Profile and Outcome of Acute Glomerulonephritis in a Tertiary Care Centre in the Eastern Nepal
| creativeworkseries.issn | ISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987 | |
| dc.contributor.author | Shah, GS | |
| dc.contributor.author | Yadav, SP | |
| dc.date.accessioned | 2026-05-13T05:05:24Z | |
| dc.date.available | 2026-05-13T05:05:24Z | |
| dc.date.issued | 2014 | |
| dc.description | GS Shah Department of Pediatrics and Adolescent Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal SP Yadav Department of Pediatrics and Adolescent Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal | |
| dc.description.abstract | Abstract Introduction: Acute glomerulonephritis (AGN) generally presents as a constellation of findings that includes hematuria, edema, and often hypertension. The study aimed to determine the clinic-biochemical profile and outcome of acute glomerulonephritis in children at tertiary care centre in the Eastern Part of Nepal. Methods: A prospective study was conducted on all the cases found to have acute glomerulonephritis, and sample size constituted all children between 1 month to 15 year, attending the Renal Special OPD and those hospitalized in pediatric department of BPKIHS from Feb. 2012 to Jan.2013 with acute glomerulonephritis. Results: There were total of 94 cases of acute glomerulonephritis (AGN), which comprise 3.1% of annual pediatric admissions. 52.1% were female and male were 47.8%. Mean age of presentation was 9.2 yrs. ±3.1 SD. Aetiology of AGN was post infectious glomerulonephritis (PIGN) 84.0%, lupus nephritis 10.6%, mumps nephritis 3.1% and HSP nephritis 2.1%. ASO titer was raised in 34.0%. 47.8% had raised urea, 43.6% had raised creatinine level, >2+ proteinuria was present in 26.6% and pyuria in 34.0%. The common clinical findings at presentation were microscopic hematuria (95.7%), hypertension (86.2%), edema (85.1%), fever(63.8%), oliguria(22.3%), pain abdomen (21.3%) and others. History of sore throat and pyoderma was present in 25.5% and 19.1% respectively. Complications at presentation were hypertensive encephalopathy (9.5%), cardiac failure (9.5%) and acute kidney injury (6.3%). Of 94 cases, 92 cases (97.8%) improved and 2 cases (2.1%) expired due to acute kidney injury. Conclusion: Acute glomerulonephritis is a significant renal problem in children and is one of the common causes of hospital admission. Early identification and comprehensive monitoring and management is required to prevent morbidity and mortality. Keywords: Children, hematuria, Acute glomerulonephritis | |
| dc.identifier | https://doi.org/10.59779/jiomnepal.564 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/6065 | |
| dc.language.iso | en_US | |
| dc.publisher | Institute of Medicine | |
| dc.subject | Children | |
| dc.subject | hematuria | |
| dc.subject | Acute glomerulonephritis | |
| dc.title | Clinical Profile and Outcome of Acute Glomerulonephritis in a Tertiary Care Centre in the Eastern Nepal | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 33 | |
| oaire.citation.startPage | 29 | |
| relation.isJournalIssueOfPublication | 29e51979-9618-4dd8-9737-216e83305d97 | |
| relation.isJournalIssueOfPublication.latestForDiscovery | 29e51979-9618-4dd8-9737-216e83305d97 | |
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