Article:
Hypertension in primary open angle glaucoma

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorPokharel, Suprada
dc.contributor.authorSherpa, Dakki
dc.contributor.authorMalla, Om Krishna
dc.creator.affiliationDepartment of Ophthalmology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal.
dc.creator.affiliationDepatment of Ophthalmology, National Academy of Medical Sciences, Kathmandu, Nepal.
dc.creator.affiliationDepartment of Ophthalmology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal.
dc.date.accessioned2026-10-08T05:22:16Z
dc.date.available2026-10-08T05:22:16Z
dc.date.issued2014
dc.description.abstractAbstract Introduction: The impact of vascular factors in POAG is well known and controversial. Some reports have shown high blood pressure in POAG, some low systolic blood pressure and some described no difference in blood pressure between POAG and controls. However decreased ocular perfusion pressure was found in most of the studies. Our study aims to assess the role of hypertension in POAG . Methods: It was cross-sectional case–control hospital based study carried out from 1st June 2012 to 1st June 2013. There were 40 cases and 100 controls included in the study. The role of hypertension were compared with those hypertensive patients with glaucoma (cases) and hypertensive patients without glaucoma (controls). Results: Age above 50 years (odds ratio: 4.827 with 95% CI 1.862-12.517), male genders (odds ratio: 3.10 with 95% CI 1.356-7.146) and low diastolic perfusion pressure (odds ratio: 3.857 with 95% CI 1.362-11.224) showed strongly positive association with POAG. High systolic blood pressure (odds ratio: 1.476 95% CI 0.627-3.476), high diastolic blood pressure (odds ratio: 1.348 95% CI 0.587-3.096) and low systolic perfusion pressure (odds ratio: 1.8661 with 95% CI 0.649- 5.335) were weakly associated with glaucoma in our study. Conclusions: Age above 50 years, male gender and low diastolic perfusion pressure were strong risk factor for the development of POAG. Keywords: Diastolic blood pressure; Diastolic perfusion pressure; POAG; Systolic blood pressure; Systolic perfusion pressure.
dc.identifier.doihttps://doi.org/10.31729/jnma.2728
dc.identifier.urihttps://hdl.handle.net/20.500.14572/8029
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectDiastolic blood pressure
dc.subjectDiastolic perfusion pressure
dc.subjectPOAG
dc.subjectSystolic blood pressure
dc.subjectSystolic perfusion pressure
dc.titleHypertension in primary open angle glaucoma
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage774
oaire.citation.startPage771
relation.isJournalIssueOfPublication3343ac2a-d3ee-4656-894b-87301f9b3449
relation.isJournalIssueOfPublication.latestForDiscovery3343ac2a-d3ee-4656-894b-87301f9b3449
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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