Publication:
Antibiotic Resistance Pattern in Intensive Care Unit of a Tertiary Care Hospital, Nepal

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creativeworkseries.issn1812-2027
dc.contributor.authorChaudhary, R
dc.contributor.authorBhatta, S
dc.contributor.authorPant, C
dc.contributor.authorPathak, P
dc.contributor.authorPhuyal, N
dc.contributor.authorShrestha, L
dc.date.accessioned2026-01-08T07:30:41Z
dc.date.available2026-01-08T07:30:41Z
dc.date.issued2024
dc.descriptionChaudhary R,1 Bhatta S,1 Pant C,2 Pathak P,3 Phuyal N,2 Shrestha L2 1Department of Microbiology 2Department of Internal Medicine 3Department of Community Medicine Nepalese Army Institute of Health Sciences Kathmandu, Nepal
dc.description.abstractABSTRACT Background Intensive care unit (ICU) is the especial department of the hospital where critically ill patients are treated with the unique type of technologies to revert back to functional by body’s own mechanism. Therefore, there are lots of external intervention with chance of getting bacterial infections. Antibiotics are medicines used to prevent and treat such bacterial infections. However, due to selective broad spectrum antibiotic pressure there is great chances to develop antimicrobial resistance at any time during hospital stay in intensive care unit. Objective To find out the antibiotic resistance pattern among Gram negative bacteria in Intensive Care Unit. Method A Descriptive cross-sectional study was conducted in Department of Microbiology of Tertiary care center for 18 months On the basis of previous sample load census method was used to include 500 sample from intensive care unit during study period. Among them only Gram negative bacteria were included in the study. All the samples were processed following standard methodology. Result Out of 500 samples, growth was observed in 451 (90.2%) samples. Among all the isolates Escherichia coli (29.6%) was predominant organism. It had shown high resistance towards Ciprofloxacin (93.5%) even in urine sample Ciprofloxacin (86.9%). Conclusion Our study showed Escherichia coli as a major organism in intensive care unit. This was resistant to commonly used oral antibiotic leaving restricted option for use of higher antibiotics. Therefore, continuous surveillance of such bacterial pathogen is warranted with implementation of effective Infection Prevention and Control measures in Health Care setting with emphasis to critical care units. KEY WORDS Antibiotic resistance, Escherichia coli, Intensive care unit
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4144
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectAntibiotic resistance
dc.subjectEscherichia coli
dc.subjectIntensive care unit
dc.titleAntibiotic Resistance Pattern in Intensive Care Unit of a Tertiary Care Hospital, Nepal
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage82
oaire.citation.startPage78
relation.isJournalIssueOfPublication5a0c1a45-42a4-4aaf-9ef8-7a7b58ab2063
relation.isJournalIssueOfPublication.latestForDiscovery5a0c1a45-42a4-4aaf-9ef8-7a7b58ab2063
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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