Publication: Analysis of Predictors of Relapse in Children with Steroid Sensitive Nephrotic Syndrome
| creativeworkseries.issn | ISSN 1990-7974 eISSN 1990-7982 | |
| dc.contributor.author | Bhatta, Mukesh | |
| dc.contributor.author | Shah, Gauri Shankar | |
| dc.contributor.author | Mishra, Om Prakash | |
| dc.date.accessioned | 2026-02-05T10:19:37Z | |
| dc.date.available | 2026-02-05T10:19:37Z | |
| dc.date.issued | 2017 | |
| dc.description | Mukesh Bhatta B.P. Koirala Institute of Health Sciences (BPKIHS) Dharan Gauri Shankar Shah B.P. Koirala Institute of Health Sciences (BPKIHS) Dharan Om Prakash Mishra Banaras Hindu University, Varanasi 221005 | |
| dc.description.abstract | Abstract: Introduction: Children with idiopathic nephrotic syndrome (INS) are steroid responsive but have relapses in subsequent non-treatment period. The objective of the present study was to analyze the factors which could predict relapses in these children. Material and Methods: Forty patients of INS aged 1-14 years of both gender were enrolled over one year period and followed for six months after treatment of initial episode of Nephrotic Syndrome. Results: The median age of children was 4.5 years and male to female ratio 1.9:1. There were 24(60%) relapses and 16(40%) non-relapses. The relapses had significantly higher mean total leukocyte count, serum urea, potassium and cholesterol than non-relapses. It was also observed that the median age of onset in relapses was significantly lower than non-relapses (p<0.001). Also, the median time to response to steroid therapy was longer in relapses than non-relapses (p<0.001). Children who relapsed had infections at the time of relapse. Conclusion: Thus, onset of disease in younger age group, late response to steroid therapy and presence of infections were found to be associated with relapses in these children. | |
| dc.identifier | https://doi.org/10.3126/jnps.v37i1.17432 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/4544 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Paediatric Society (JNPS) | |
| dc.subject | Nephrotic syndrome | |
| dc.subject | Factors | |
| dc.subject | Relapses | |
| dc.title | Analysis of Predictors of Relapse in Children with Steroid Sensitive Nephrotic Syndrome | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 4 | |
| oaire.citation.startPage | 1 | |
| relation.isJournalIssueOfPublication | 746230eb-c5af-4ac2-aa4b-ea6e90b44c32 | |
| relation.isJournalIssueOfPublication.latestForDiscovery | 746230eb-c5af-4ac2-aa4b-ea6e90b44c32 | |
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