Publication: Role of CaCO3 alone and CaCO3 plus Vitamin D3 in terms of Calcium Phosphorus Product in Chronic Kidney Diseases
Date
2011
Authors
Article Type
Original Article
Journal Title
Journal ISSN
1999-6217
Volume Title
Publisher
Nepal Health Research Council
Abstract
Background: CaCO3 alone and CaCO3 plus vitamin D3 metabolites are commonly prescribed in CKD patients.
The objective of this study is to analyze the changes in Ca x P product, calcium level and phosphorus level in CKD patients receiving calcium carbonate alone and calcium carbonate with vitamin D3 in combination.
Methods: A prospective, cross sectionalstudy among CKD patients under maintenance hemodialysis two times a week were studied over a period of one year. The patients were divided into two groups receiving oral CaCO3 alone and CaCO3 plus vitamin D3 once a day. The patients were followed for 1 month and result of Ca x P product was analyzed accordingly.
Results: Mean decrease of Ca x P product in CaCO3 group is (50.42+/-8.85 to 47 +/-6.63) in one month, p value =0.001(0.6-5) and CI- 95%. There is also significant reduction of phosphorus level in CaCO3 group than CaCO3 plus vitamin D3 group. Mean decrease in phosphorus in CaCO3 group is (5.51+/-0.76 to 5.17+/- 0.05) in one month. P value =0.01(0.14-0.53) and CI 95%.
Conclusions: There is a significant decrease in Ca x P product and phosphorus level was observed in CKD patients taking CaCO3 alone.
Keywords: calcium carbonate, calcium phosphorus product, chronic kidney disease, vitamin.
Description
Keywords
Calcium carbonate, Calcium phosphorus product, Chronic kidney disease, Vitamin
Identifier
https://doi.org/10.33314/jnhrc.v0i0.258
Citation
AdhikaryL., AcharyaS., & AcharyaL. (2011). Role of CaCO3 alone and CaCO3 plus Vitamin D3 in terms of Calcium Phosphorus Product in Chronic Kidney Diseases. Journal of Nepal Health Research Council. https://doi.org/10.33314/jnhrc.v0i0.258