Article:

Tardive dystonia: a troublesome side-effect of conventional antipsychotic medicines

Abstract Tardive dystonia is a frustrating condition encountered after prolonged use of conventional dopamine receptor antagonist drugs. The present case report illustrates the development of tardive dystonia after 24 months of continuous use of haloperidol, which was managed well with olanzapine and tetrabenzine in combination. Less promising outcome of various treatment modalities is discussed and cautious use of dopamine receptor antagonist drugs is advocated. Keywords: tardive dystonia, dopamine receptor antagonist, tetrabenazine, olanzapine