Publication: Dexamethasone Pulse Therapy in Pemphigus Vulgaris Associated Myocardial Infarction in Resource-Limited Settings
| creativeworkseries.issn | ISSN 2091-0231 eISSN 2091-167X | |
| dc.contributor.author | Paudel, Vikash | |
| dc.date.accessioned | 2025-09-23T10:02:47Z | |
| dc.date.available | 2025-09-23T10:02:47Z | |
| dc.date.issued | 2022 | |
| dc.description | Vikash Paudel National Medical College and Teaching Hospital, Birgunj, Nepal https://orcid.org/0000-0001-8729-052X | |
| dc.description.abstract | Abstract: Pemphigus vulgaris is an autoimmune blistering disorder where biologics are the cornerstone of therapy. In resource-limited settings, a dermatologist should rely on systemic steroids. Dexamethasone pulse therapy is a cheap and established treatment of pemphigus where a supra-pharmacological dose of dexamethasone is used. High dose of dexamethasone is supposed to have atherogenic potential which could promote a hypercoagulable state. Here, we report a case of a 30-year-old woman in the resource-limited setting of Nepal, who was under monthly dexamethasone pulse therapy for pemphigus vulgaris, who had an acute episode of ST-segment elevated myocardial infarction. In such setting, although steroids are the cornerstone of therapy in various disorders, physicians should be equally cautious in using a high dose of steroids which might lead to fatal complications. This could probably be the first case report of steroid-induced acute myocardial infarction during treatment of pemphigus worldwide. | |
| dc.identifier | https://doi.org/10.3126/njdvl.v20i1.43296 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/2302 | |
| dc.language.iso | en_US | |
| dc.publisher | Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) | |
| dc.subject | Dexamethasone | |
| dc.subject | Myocardial Infarction | |
| dc.subject | Pemphigus vulgaris | |
| dc.subject | Pulse therapy | |
| dc.title | Dexamethasone Pulse Therapy in Pemphigus Vulgaris Associated Myocardial Infarction in Resource-Limited Settings | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Letters to the Editor | |
| oaire.citation.endPage | 63 | |
| oaire.citation.startPage | 62 | |
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